A Patient with Systemic Lupus Erythematosus (SLE) Shows Evidence of Decreased

A patient with systemic lupus erythematosus (SLE) shows evidence of decreased hemoglobin and ongoing hemolysis. The DAT is negative. Which of the following is the most likely explanation for these results?

A) The subclass of IgG is not recognized by the polyspecific AHG.
B) The thermal amplitude of the antibody is <37°C.
C) High-dose IVIG used in treatment is interfering with the binding of AHG.
D) There is insufficient IgG for detection.

Correct Answer:

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