Question 1

Activation of factor ___ serves as a common link between the component parts of the homeostatic mechanism: blood coagulation,fibrinolytic,kinin,and complement systems.

Accepted Answer

A)   II
B)   V
C)   VII
D)   XII D

Question 2

Which of the following is/are true of platelets?

Accepted Answer

A)   Platelets have a nucleus.
B)   There is a reserve of platelets in the microvasculature or spleen.
C)   Platelets are derived from polymorphonuclear leukocytes (PMNs) .
D)   a, b, and c
E)   a and c B

Question 3

Use of which of the following medications is recommended if major surgery must be performed under emergency conditions for a patient receiving aspirin therapy?

Accepted Answer

A)   ticlopidine
B)   desmopressin
C)   abciximab
D)   tranexamic acid B

Question 4

Which of the following screening tests is used to check the extrinsic pathway (factor VII)and the common pathway (factors V and X,prothrombin,and fibrinogen)?

Accepted Answer

A)   thrombin time
B)   prothrombin time
C)   partial thromboplastin time
D)   platelet count

Question 5

Which of the following clinical laboratory tests is used to screen patients for thrombocytopenia?

Accepted Answer

A)   PT
B)   aPTT
C)   TT
D)   platelet count

Question 6

Tissue-type plasminogen activator (tPA)is released by _________ cells at the site of injury.

Accepted Answer

A)   endothelial
B)   mesenchymal
C)   plasma
D)   polymorphonuclear leukocytes (PMNs)

Question 7

Warfarin anticoagulation therapy should be continued prior to minor oral surgery and other similarly invasive dental procedures if the INR is __ or less.

Accepted Answer

A)   2.5
B)   3.5
C)   4.5
D)   5.5

Question 8

Which of the following is the single best screening test for coagulation disorders?

Accepted Answer

A)   platelet count
B)   thrombin time
C)   prothrombin time
D)   partial thromboplastin time

Question 9

Which of the following is the most common cause of arterial thrombosis?

Accepted Answer

A)   malignancy
B)   atherosclerosis
C)   disseminated intravascular coagulation (DI
C)  
D)   hormonal therapy

Question 10

Which of the following is the best laboratory test to monitor patients using warfarin?

Accepted Answer

A)   BT
B)   PT
C)   aPTT
D)   INR

Question 11

Vitamin K is needed by the liver to produce factor ___.

Accepted Answer

A)   II
B)   V
C)   VIII
D)   XI

Question 12

Which of the following three tests are recommended for use by the dentist in initial screening for possible bleeding disorders?

Accepted Answer

A)   Ivy bleeding time (BT) , platelet function analyzer (PFA-100) , and prothrombin time (PT) 
B)   Ivy bleeding time (BT) , prothrombin time (PT) , and platelet count
C)   activated partial thromboplastin time (aPTT) , prothrombin time (PT) , and platelet count
D)   platelet function analyzer (PFA-100) , activated partial thromboplastin time (aPTT) , and prothrombin time (PT)

Question 13

Routine dental treatment involving minor tissue injury should be delayed if the platelet count is below _______/µL.

Accepted Answer

A)   10,000
B)   30,000
C)   50,000
D)   70,000

Question 14

Which of the following is the most popular antiplatelet drug?

Accepted Answer

A)   clopidogrel
B)   dipyridamole
C)   eptifibatide
D)   aspirin

Question 15

Most bleeding disorders are ________.

Accepted Answer

A)   due to a platelet deficiency
B)   due to a deficiency in von Willebrand factor
C)   due to Hemophilia A
D)   iatrogenic

Question 16

Which of the following medications is the best choice for postoperative pain control in a patient taking warfarin (Coumadin)?

Accepted Answer

A)   celecoxib
B)   acetaminophen
C)   aspirin
D)   ibuprofen

Question 17

Which of the following is/are true of disseminated intravascular coagulation (DIC)?

Accepted Answer

A)   The most common cause of DIC worldwide is snakebite.
B)   The major clinical problem with DIC is thrombosis.
C)   DIC is a condition that results when the clotting system is activated in all or a major part of the vascular system.
D)   a, b, and c
E)   a and c

Question 18

A platelet count is very effective for identifying patients who have ________.

Accepted Answer

A)   von Willebrand disease
B)   Glanzmann disease
C)   thrombocytopenia
D)   uremia

Exam 24: Acquired Bleeding and Hypercoagulable Disorders