Question 1

Regulatory secretion of hormones would be associated with ________ at the transface of the Golgi.

Accepted Answer

A)  endosomes
B)  lysosomes
C)  clathrin-coated vesicles
D)  non-clathrin vesicles
E)  microsomes C

Question 2

Oxidation of very long fatty acids occurs in the

Accepted Answer

A)  mitochondria.
B)  peroxisomes.
C)  lysosomes.
D)  smooth endoplasmic reticulum.
E)  residual bodies. B

Question 3

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

Accepted Answer

Smooth endoplasmic reticulum

Question 4

All of the following are true about botulinum toxin/Botox except

Accepted Answer

A)  The toxin is one of the most potent toxins known.
B)  Botox is a SNARE protein.
C)  It can be used therapeutically to stop muscle spasms.
D)  It has been used to remove wrinkles caused by muscle contractions.
E)  It has potential use as a migraine headache treatment.

Question 5

Which of the following organelles are not part of the endomembrane system?

Accepted Answer

A)  peroxisomes
B)  Golgi complexes
C)  smooth endoplasmic reticulum
D)  endosomes
E)  rough endoplasmic reticulum

Question 6

A radioactively labeled protein is made by cells and followed through the various organelles in the secretory pathway.After six hours,all of the radioactivity is still primarily in the Golgi apparatus.This suggests that the

Accepted Answer

A)  protein was not translated by the ribosomes.
B)  protein does not possess a signal peptide for localization within the lumen of the rough endoplasmic reticulum.
C)  protein possesses a signal for localization within the Golgi apparatus.
D)  all of the above

Question 7

Compared with the trans-Golgi proteins,the cis-Golgi proteins would

Accepted Answer

A)  be identical.
B)  be shorter in length.
C)  be glycosylated and contain amino acid modifications.
D)  contain sialic acid.
E)  be glycosylated only.

Question 8

The chronic use of the ________ class of drugs can result in decreased effectiveness of antibiotics,anticoagulants,and steroids.

Accepted Answer

The answer of The chronic use of the ________ class...

Question 9

Design an experiment that will allow you to follow a protein from the endoplasmic reticulum,Golgi complex,and secretion vesicles to the outside of the cell.How will this differ if the protein is localized within lysosomes?

Accepted Answer

The answer of Design an experiment that will allow you...

Question 10

In a lysosomal storage disease,the hydrolases of lysosomes are released from the cells,rather than being isolated into vesicles.What is one possible mechanism for this result?

Accepted Answer

A)  A proton gradient within vesicles was not generated.
B)  The ER was unable to produce lysosomal vesicles.
C)  Lysosomal enzymes were not phosphorylated in the rER.
D)  There is a lack of mannose-6-phosphatase activity.
E)  There is a mutation in all hydrolase genes that results in loss of the signal peptide.

Question 11

A ________ is a short sequence of amino acids that targets a protein for translation across the endoplasmic reticulum.

Accepted Answer

The answer of A ________ is a short sequence of...

Question 12

A protein that is N-glycosylated is expected to

Accepted Answer

A)  be secreted from the cell.
B)  be localized in the endoplasmic reticulum.
C)  be localized in the Golgi body.
D)  eventually become an endosome.
E)  eventually become a peroxisome.

Question 13

Distinguish among the following: endocytosis,pinocytosis,and phagocytosis.

Accepted Answer

The answer of Distinguish among the following: endocytosis,pinocytosis,and phagocytosis....

Question 14

All of the following are part of the endomembrane system,except the

Accepted Answer

A)  Golgi body.
B)  endosomes.
C)  lysosomes.
D)  peroxisomes.
E)  Neither C nor D are part of the endomembrane system.

Question 15

Exocytosis is stimulated by regional increases in ________ concentration.

Accepted Answer

The answer of Exocytosis is stimulated by regional increases in...

Question 16

All of the following are unique to plant cells except

Accepted Answer

A)  leaf peroxisomes.
B)  glyoxysomes.
C)  nodule peroxisomes.
D)  peroxisomes.
E)  chloroplasts.

Question 17

V-________ and t-________ mediate final docking between target and vesicle.

Accepted Answer

The answer of V-________ and t-________ mediate final docking between...

Question 18

If you were wanting to synthesize a particular protein in plants that allowed it to accumulate within the plant vacuole,how would you design your chimeric protein to concentrate within this vacuole? What features of the plant vacuole are unique?

Accepted Answer

The answer of If you were wanting to synthesize a...

Question 19

The continuous release of mucus by the epithelial cells lining the respiratory tract is an example of

Accepted Answer

A)  regulated secretion.
B)  constitutive secretion.
C)  the mucus response.
D)  the formation of clathrin-coated pits.
E)  phagocytosis.

Question 20

All of the following are part of the core oligosaccharide side chain in the ER,except

Accepted Answer

A)  N-acetyl glucosamine.
B)  erythrose.
C)  mannose.
D)  glucose.
E)  both choices A and C

Exam 12: The Endomembrane System and Peroxisomes