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In Fragile X Syndrome, Only Noncoding Regions Within the Gene

Question 2

Multiple Choice

In fragile X syndrome, only noncoding regions within the gene for a protein that directs and maintains brain development are heavily methylated, resulting indecreasedcognitive ability and behavioral problems. What is the most likely mechanism of this abnormal expression?


A) Increased microRNA molecules reducing the synthesis of the gene product
B) Failure of the methylated regions to undergo translation
C) Suppression of the "splicing out" action for introns
D) Suppression of promoter function

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