How Does Histone Modification Alter Gene Expression

How does histone modification alter gene expression?

A) Modified histones result in increased DNA methylation, which increases the transcription of genes in that area.
B) In areas where histones are modified, the DNA is more tightly wound, and genes are not transcribed.
C) Histone modification results in an increase in microRNA production, which inhibits gene expression by preventing translation.
D) Histone modification results in an increase in microRNA production, which promotes gene expression by enhancing translation.

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