A Patient with Second-Degree Burns Is Treated with Silver Sulfadiazine

A patient with second-degree burns is treated with silver sulfadiazine [Silvadene]. A nursing student asks the nurse about the differences between silver sulfadiazine and mafenide [Sulfamylon], because the two are similar products, and both contain sulfonamides. What does the nurse tell the student about silver sulfadiazine?

A) It causes increased pain when the medication is applied.
B) It has a broader spectrum of antimicrobial sensitivity.
C) It has antibacterial effects related to release of free silver.
D) It suppresses renal excretion of acid, causing acidosis.

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