Question 1

One of the following is used as a pH dependent controlled release excipient.

Accepted Answer

A)  Carnauba wax
B)  HPMC Phthalate
C)  Methyl cellulose
D)  Glyceryl Monostearate B

Question 2

A water soluble substance used as coating material in microencapsulation process is:

Accepted Answer

A)  Polyethylene
B)  Silicone
C)  HEC
D)  Paraffin C

Question 3

Which of the following industrial dryer is used to dry tablet granules?

Accepted Answer

A)  Drum Dryer
B)  Fluid dryer
C)  Spray dryer
D)  Freeze Dryer B

Question 4

Durability of a tablet to combined effects of shock and abrasion is evaluated by using.

Accepted Answer

A)  Hardness tester
B)  Disintegration test apparatus
C)  Friabilator
D)  Screw gauge

Question 5

A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is.

Accepted Answer

A)  HPMC
B)  CAP
C)  Polyethylene
D)  Carnauba wax

Question 6

Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in.

Accepted Answer

A)  0.1N HCl
B)  Phosphate buffer
C)  water
D)  0.1 M H2SO4

Question 7

According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?

Accepted Answer

A)  1%
B)  2%
C)  4%
D)  5%

Question 8

Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets?

Accepted Answer

A)  Dicalcium Phosphate
B)  Microcrystalline cellulose
C)  Starch
D)  Lactose

Question 9

What is Primogel?

Accepted Answer

A)  Substituted HPMC for direct compression
B)  Modified MCC for direct compression
C)  Hydrogelling polymer for gel formation
D)  Modified starch for disintegration

Exam 5: Pharmaceutical Formulation and Processing