Question 1

Which of the following drugs has a high extraction ratio?

Accepted Answer

A) Diazepam 
B) Theophylline 
C) Phenytoin 
D) Warfarin 
E) Propranolol

Question 2

Bioavailability is

Accepted Answer

A) The difference between the amount of drug absorbed and the amount excreted 
B) The proportion of the drug in a formulation that is found in the systemic circulation 
C) The AUC relating plasma concentration of drug to time after administration 
D) Always identical with different formulations of the same drug 
E) A measure of the rate of absorption of a drug

Question 3

Which is the safest to give in pregnancy?

Accepted Answer

A) Lithium 
B) Phenytoin 
C) Gentamycin 
D) Heparin 
E) ACE inhibitors

Exam 1: Pharmacokinetics and Drug Properties

Which of the following drugs has a high extraction ratio?

Bioavailability is

Which is the safest to give in pregnancy?