Multiple Choice
The translocation that places the transcription factor Tel at the amino terminus of the PDGF receptor converts PDGFR to an oncogene by
A) constitutive repression of the fusion protein.
B) forming Tel dimers that produce unregulated signals for proliferation.
C) activating the tyrosine kinase domain in monomeric form.
D) increasing the transcriptional activation capability of Tel.
Correct Answer:
Verified
Correct Answer:
Verified
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