A 28-Year-Old Woman Is Brought to the Physician Because of Progressive

A 28-year-old woman is brought to the physician because of progressive difficulty walking, slowed speech, and a tremor for the past 5 months. Medical history is notable for depression over the past year.  Her grandfather died of bleeding esophageal varices at the age of 42 years. She does not drink alcohol. She is alert and oriented but has a flat affect. Her speech is slurred and monotonous. Examination shows a broad-based gait and a low-frequency tremor of her left hand. Abdominal examination shows hepatosplenomegaly. The most likely cause of this patient's condition is an abnormality in which of the following physiologic processes?

A) Biliary excretion
B) Immunoglobulin production
C) Intestinal absorption
D) Lipid metabolism
E) Renal tubular reabsorption

Correct Answer:

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