A 65-Year-Old Guy Arrives at the Clinic After Experiencing 2

A 65-year-old guy arrives at the clinic after experiencing 2 months of fatigue and a chronic, unproductive cough. He has a history of coronary artery disease and a heart attack. He underwent broad local excision of a melanoma on his posterior neck three years ago. The patient has a smoking history of 50 packs per year. The vital indicators are within normal ranges. A chest radiograph shows several lung abnormalities as well as hilar lymphadenopathy. After staining with hematoxylin and eosin, histopathology from one of the biopsied lung lesions is shown below. These histopathologic findings are most consistent with which of the following diagnoses?

A) Chronic systolic heart failure
B) Emphysema
C) Hodgkin lymphoma
D) Metastatic melanoma
E) Sarcoidosis
F) Squamous cell lung cancer

Correct Answer:

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