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A 4-Year-Old Girl with an Inwardly Deviated Right Eye Is

Question 537

Multiple Choice

A 4-year-old girl with an inwardly deviated right eye is brought to the clinic. In comparison to the left eye, the right eye exhibits a paler red response upon examination. The retina contains a well-circumscribed white mass, as seen on dilated funduscopic examination. Genetic testing reveals that the mass was caused by a germline mutation in the patient's cells.   Which of the following is the most likely function of the protein affected by this patient's gene mutation?


A) Activation of receptor tyrosine kinase
B) Conversion of GTP to GDP
C) Opposition of p53 activity
D) Prevention of the G1/S cell cycle transition
E) Repair of damaged DNA

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