A 54-Year-Old Man Presents with an Enlarged Supraclavicular Lymph Node

A 54-year-old man presents with an enlarged supraclavicular lymph node on the left side. On palpation, the node is painless and stony hard. The node biopsy reveals anaplastic cells that are keratin positive. Which of the following is the most likely origin of the cells detected on the biopsy?

A) Lymphocytes
B) Epithelial surfaces
C) Muscle tissue
D) Endothelium
E) Glial cells

Correct Answer:

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