A 12-Month-Old Boy Is Evaluated for an Eczematous Rash

A 12-month-old boy is evaluated for an eczematous rash.  Medical history is significant for several severe respiratory infections that required hospitalization.  Complete blood count shows white blood cells at 9,000/mm³ and platelets at 40,000/mm³.  The platelets seem abnormally small and deformed on the peripheral blood smear.  Which of the following is the most likely diagnosis?

A) Aplastic anemia
B) Ataxia telangiectasia syndrome
C) Chédiak-Higashi syndrome
D) DiGeorge syndrome
E) Hemolytic uremic syndrome
F) Wiskott-Aldrich syndrome

Correct Answer:

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