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Walking for 6 Minutes Causes Mild Dyspnea, and Oxygen Saturation

Question 191

Multiple Choice

Walking for 6 minutes causes mild dyspnea, and oxygen saturation drops to 88%.  Chest x-ray shows no infiltrates.  Pulmonary function testing reveals FEV1 at 95% of predicted and a FEV1/FVC ratio of 84%.  Pulmonary artery systolic pressure estimated by Doppler echocardiography is 65 mm Hg at rest (normal 15-30 mm Hg) .
Lung biopsy will most likely demonstrate which of the following?


A) Alveolar spaces filled with fibroblasts
B) Arterial intimal hyperplasia
C) Bronchial wall thickening and mucus plugs
D) Chronic inflammation with noncaseating granulomas
E) Septal widening and hemosiderin-loaded macrophages

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