Physiologists Are Studying the Forces Governing Glomerular Ultrafiltration Using a Single

Physiologists are studying the forces governing glomerular ultrafiltration using a single nephron in an intact kidney of an experimental animal.  Hydrostatic pressure in the glomerular capillary and Bowman space is measured using micropipette transducers.  Colloid osmotic pressure in the glomerular capillary is estimated using the difference in plasma protein concentration in the afferent and efferent arterioles.  The glomerular surface is assumed to be functionally intact with negligible filtration of plasma proteins into the Bowman space.  From the data obtained, net filtration pressure is calculated at 10 mm Hg.  A substance is instilled into the renal artery, and measurements are repeated.  The net filtration pressure after the intervention is 20 mm Hg.  Which of the following substances was most likely used in this experiment?

A) Albumin concentrate
B) Alpha-adrenergic agonist
C) Angiotensin II agonist
D) Prostaglandin inhibitor
E) Vasopressin 2 antagonist

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