A 55-Year-Old Nurse Was Started on Multidrug Therapy 3 Weeks

A 55-year-old nurse was started on multidrug therapy 3 weeks ago to treat pulmonary tuberculosis contracted from a former patient.  He comes to his primary care provider due to fatigue and low-grade fever for several days.  He also has had muscle aches and severe joint pain in his elbows, wrists, and knees.  The patient says, "I don't think it's the flu; I had the vaccine months ago."  He has no current respiratory symptoms apart from pleuritic chest pain.  The patient has no other significant past medical or family history.  His examination is unremarkable. Laboratory results are as follows: An abnormality in which of the following metabolic processes most likely underlies this patient's current condition?

A) Liver acetylation
B) Liver hydrolysis
C) Liver hydroxylation
D) Liver sulfate conjugation
E) Plasma hydrolysis
F) Unchanged excretion

Correct Answer:

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