A 23-Year-Old Man Is Evaluated for Excessive Bruising Since Childhood

A 23-year-old man is evaluated for excessive bruising since childhood.  He says some of his family members "bleed easily" and sometimes require blood transfusions.  Temperature is 36.7 C (98.1 F) .  Physical examination is unremarkable.  Complete blood cell count is unremarkable.  Platelet aggregometry is abnormal.  Genetic testing identifies a defect in a platelet surface glycoprotein receptor that normally binds fibrinogen to support platelet aggregation.  The abnormal glycoprotein receptor found in this patient is most likely targeted by which of the following medications?

A) Abciximab
B) Argatroban
C) Aspirin
D) Clopidogrel
E) Dabigatran
F) Heparin
G) Warfarin

Correct Answer:

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