A 62-Year-Old Woman Is Evaluated for Refractory Nausea and Vomiting

A 62-year-old woman is evaluated for refractory nausea and vomiting.  She was recently diagnosed with ovarian cancer and underwent total hysterectomy with bilateral salpingo-oophorectomy and pelvic lymph node dissection.  The patient was started on highly emetogenic adjuvant chemotherapy.  Despite taking ondansetron around the clock, she continues to have nausea and vomiting.  She has no abdominal pain or constipation.  Vital signs are normal.  Examination shows a well-healed abdominal scar.  There is no tenderness or abnormal masses.  Bowel sounds are normal.  Additional therapy blocking which of the following receptors would most likely be helpful in this patient?

A) Endogenous opioid
B) Motilin
C) Neurokinin 1
D) Neuropeptide Y
E) Nicotinic acetylcholine

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free