A 38-Year-Old Man Comes to the Emergency Department with Severe

A 38-year-old man comes to the emergency department with severe abdominal pain and vomiting.  The pain radiates to his back and improves by bending forward.  Physical examination shows tenderness over the epigastrium and decreased bowel sounds.  The patient is admitted to the hospital and treated with intravenous fluids and pain medication, but his condition fails to improve.  An abdominal CT scan reveals diffuse pancreatic enlargement with areas of necrosis.  The inappropriate activation of which of the following most likely initiated this patient's condition?

A) Amylase
B) Chymotrypsinogen
C) Lipase
D) Proelastase
E) Prophospholipase
F) Trypsinogen

Correct Answer:

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