A Group of Researchers Is Studying Population-Based Screening Interventions to Reduce

A group of researchers is studying population-based screening interventions to reduce mortality from abdominal aortic aneurysm.  This disorder develops primarily in elderly patients and is often asymptomatic until an acute rupture event, which is frequently fatal.  Screening of high-risk patients for abdominal aortic aneurysm is found to reduce mortality.  Which of the following risk factor combinations would likely define the highest-risk group for screening purposes?

A) Diabetes, smoking
B) Female, hyperlipidemia
C) Female, hypertension
D) Hyperlipidemia, hypertension
E) Male, diabetes
F) Male, smoking

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