A 65-Year-Old Man Comes to the Office Due to Several

A 65-year-old man comes to the office due to several weeks of nonproductive cough.  The patient also has anorexia and unintentional weight loss.  His medical history includes hypothyroidism due to Hashimoto thyroiditis and a 50-pack-year smoking history.  Examination shows an enlarged right supraclavicular lymph node.  Imaging reveals a large mediastinal mass causing tracheal deviation.  The enlarged node is biopsied, and microscopy demonstrates clusters of small, ovoid cells with scant cytoplasm and a high mitotic count.  Immunohistochemical staining is positive for chromogranin.  This patient most likely has which of the following conditions?

A) Adenocarcinoma
B) Hodgkin lymphoma
C) Papillary thyroid carcinoma
D) Small cell cancer
E) Squamous cell cancer

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free