A 53-Year-Old Man Comes to the Physician with Progressively Worsening

A 53-year-old man comes to the physician with progressively worsening anorexia and abdominal discomfort.  He has lost 14 kg (31 lb) since the onset of his symptoms about 4 months ago.  Physical examination demonstrates nontender hepatomegaly.  Laboratory studies show an elevated serum alkaline phosphatase level and a marginally elevated alanine aminotransferase level.  A CT scan of the abdomen with oral and intravenous contrast is shown below. Which of the following is the most likely diagnosis?

A) Hepatic adenoma
B) Hepatic angiosarcoma
C) Hepatoblastoma
D) Hepatocellular carcinoma
E) Intrahepatic cholangiocarcinoma
F) Metastatic liver disease

Correct Answer:

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