A 70-Year-Old Man Comes to the Office Due to Abdominal

A 70-year-old man comes to the office due to abdominal pain that began 1 month ago.  He has also experienced fatigue and weight loss.  He has no chronic medical conditions and takes no daily medications.  The patient worked in a factory that produced polyvinyl chloride for several decades and is now retired.  Physical examination shows hepatomegaly.  Imaging demonstrates a liver mass, which is subsequently resected.  Immunohistochemical staining of the tumor cells is positive for CD31.  Which of the following is the most likely diagnosis?

A) Cavernous hemangioma
B) Cholangiocarcinoma
C) Hepatic angiosarcoma
D) Hepatoblastoma
E) Hepatocellular adenoma
F) Kaposi sarcoma

Correct Answer:

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