A Researcher Is Investigating Factors Affecting Adrenal Hormone Synthesis and Release

A researcher is investigating factors affecting adrenal hormone synthesis and release.  An intact adrenal gland is obtained from a donor cadaver, and a histologic section through the entire gland is shown below.  Cells from a specific part of the gland, indicated by the arrow, are extracted for further analysis. These cells are most likely to be directly activated by which of the following substances?

A) Acetylcholine
B) ACTH
C) Angiotensin II
D) Epinephrine
E) Norepinephrine

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