A Study Aims to Investigate the Effectiveness of the Topical

A study aims to investigate the effectiveness of the topical application of tetracycline ointment in the prevention of surgical-site infection associated with resection of advanced oral cavity cancer.  Fifty patients who underwent locoregional resection were assigned by chance to receive standard care alone or tetracycline-ointment in addition to standard care.  The patients were then followed for 1 month and the number and severity of surgical-site infections were recorded for each group.  Which of the following best describes the study design?

A) Case-control study
B) Crossover design
C) Prospective cohort study
D) Randomized control trial
E) Retrospective cohort study

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