Researchers Are Interested in the Association Between Colorectal Carcinoma and Nonsteroidal

Researchers are interested in the association between colorectal carcinoma and nonsteroidal anti-inflammatory drug use.  They first interview a group of patients with biopsy-proven colorectal carcinoma and then interview a group consisting of the patients' neighbors who are of similar age and race.  The analysis is based on comparing the results of pairs of individuals (one from each of the 2 groups) who have similar characteristics.  This design technique best helps address which of the following potential problems with this study?

A) Ascertainment bias
B) Confounding
C) Observer bias
D) Recall bias
E) Selection bias

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