A 31-Year-Old Man Comes to the Office for a Routine

A 31-year-old man comes to the office for a routine checkup.  He has no significant medical problems and does not take any medications.  The patient works as a fitness trainer and lifts weights recreationally.  He has been consuming carbohydrate-rich food prior to his weightlifting sessions and claims that it increases muscle strength.  A literature review shows that the rate of glycogenolysis within myocytes increases several hundredfold during active skeletal muscle contraction.  Which of the following substances is most likely responsible for increasing the reaction rate during active contraction?

A) ATP
B) Ca²⁺
C) cAMP
D) Glucose-6-phosphate
E) Lactate

Correct Answer:

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