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An Autopsy Is Being Performed on a 4-Year-Old Boy Who

Question 137

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An autopsy is being performed on a 4-year-old boy who recently died from a myocardial infarction.  The child had a history of intellectual disability.  Autopsy shows a prominent forehead and broad nose.  There is a diffuse haze over the corneas bilaterally.  The heart, liver, and spleen are enlarged.  Sampling of the coronary arteries is most likely to reveal intimal accumulation of which of the following substances?


A) Cholesterol
B) Glucocerebroside
C) Glycogen
D) Heparan sulfate
E) Sphingomyelin

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