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An 18-Year-Old,5'6",125 Lb Female Patient Was Admitted to the Hospital

Question 10

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An 18-year-old,5'6",125 lb female patient was admitted to the hospital 2 days ago for spinal meningitis.She developed sepsis and suffered hypercapnic respiratory failure.The patient was intubated and placed on volume-controlled continuous mandatory ventilation (VC-CMV) ,respiratory frequency (f) 12 breaths/min,tidal volume (Vᴛ) 600 mL,positive end-expiratory pressure (PEEP) 5 cm H₂O,fractional inspired oxygen (FɪO₂) 0.40.Twenty-four hours later,the patient's oxygen requirements have dramatically increased and her lung compliance has dramatically dropped,while her chest X-ray showed development of bilateral fluffy infiltrates.The most appropriate actions to take include which of the following?


A) Keep Vᴛ the same, increase f to 25 breaths/min, increase PEEP to 12 cm H₂O.
B) Decrease Vᴛ to 250 mL, increase f to 15 breaths/min, increase PEEP to 15 cm H₂O.
C) Increase Vᴛ to 550 mL, decrease f to 8 breaths/min, increase PEEP to 10 cm H₂O.
D) Decrease Vᴛ to 400 mL, decrease f to 8 breaths/min, decrease PEEP to 3 cm H₂O.

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