A 45-Year-Old,73-Inch-Tall,200 Lb Male Patient Is Admitted to the Emergency

A 45-year-old,73-inch-tall,200 lb male patient is admitted to the emergency department with an exacerbation of myasthenia gravis.The respiratory therapist assesses the patient and finds the patient's maximum inspiratory pressure is 15 cm H₂O and his vital capacity is 1200 mL.It is decided that the patient requires ventilatory support.The most appropriate ventilator settings for this patient are which of the following?

A) Pressure support ventilation (PSV) 5 cm H₂O, continuous positive airway pressure (CPAP) 10 cm H₂O, FɪO₂ 0.50
B) Pressure-controlled continuous mandatory ventilation (PC-CMV) , f = 16 breaths/min, peak inspiratory pressure (PIP) = 35 cm H₂O, positive end-expiratory pressure (PEEP) 3 cm H₂O, fractional inspired oxygen (FɪO₂) 0.45
C) Noninvasive positive pressure ventilation-bilevel positive airway pressure (NPPV-BiPAP) , f = 14 breaths/min, inspiratory positive airway pressure (IPAP) = 28 cm H₂O, expiratory positive airway pressure (EPAP) = 5 cm H₂O, FɪO₂ 0.30
D) Volume-controlled intermittent mandatory ventilation (VC-IMV) , f = 12 breaths/min, tidal volume (Vᴛ) = 725 mL, PSV 5 cm H₂O, PEEP 5 cm H₂O, FɪO₂ 0.24

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