Which of the Following Reasons Explains Why Map Units on a Chromosome

Which of the following reasons explains why map units on a chromosome linkage map are not reliable measures of physical distances?

A) The frequency of crossing over varies along the length of the chromosome.
B) The relationship between recombination frequency and map units is different in every individual.
C) Physical distances between genes change during the course of the cell cycle.
D) The gene order on the chromosomes is slightly different in every individual.

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