Multiple Choice
Using genetic engineering techniques,which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?
A) fuse it to GFP
B) add an amino acid that would get a mannose-6-phosphate group added to its carbohydrate
C) add a KDEL sequence near its C-terminus
D) mutate one of the asparagines that is normally glycosylated to an alanine,which is not glycosylated
E) None of these would cause the protein to accumulate in the ER.
Correct Answer:
Verified
Correct Answer:
Verified
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