Multiple Choice
In a lysosomal storage disease,newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes.What is one possible mechanism for this result?
A) The cis-Golgi network lacks a proton gradient.
B) The ER is unable to produce lysosomal vesicles.
C) Lysosomal enzymes are not phosphorylated in the rER.
D) Mannose is not phosphorylated in the cis-Golgi network.
E) All the hydrolase genes are mutated,resulting in synthesis by ribosomes free in the cytoplasm rather than on the endoplasmic reticulum membrane.
Correct Answer:
Verified
Correct Answer:
Verified
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