Exam 3: Bioenergetics,enzymes and Metabolism

If ATP is present in relatively high amounts,what is likely to happen to the rate of glycolytic activity in that cell?

Glycolysis occurs in the ________; the Krebs (TCA)cycle occurs in the ______ of eukaryotes and the ______ of prokaryotes.

A reaction involving the gain of one or more electrons is a(n)_________ reaction.

If a reaction vessel is cold to the touch and the reaction results in an increase in order in the reaction vessel,is the reaction spontaneous or nonspontaneous? Explain your answer.

Where is S.aureus usually found in humans? What kind of hospitalized patients develop life-threatening S.aureus infections? Distressingly,instead of just showing up in hospitals,methicillin-resistant S.aureus (MRSA)is showing up in other places.What are some examples?

What is unusual about the mechanism by which vancomycin inhibits transpeptidation of the bacterial cell wall? Why is it more difficult for bacteria to develop resistance to vancomycin than to other antibiotics?

Why was methicillin developed?

What kind of inhibitor binds very tightly to an enzyme often forming a covalent bond with an amino acid in the active site?

You are studying metabolic pathways and discover that two pathways intersect so that the enzyme basinase participates in both of the intersecting pathways,in one case using substrate K and in the other using substrate M.When presented with substrate K in amounts significantly larger than M,basinase converts K to L which leads eventually to the production of the end product R.The activity of the second pathway is depressed simultaneously.In the presence of large amounts of substrate M and lower amounts of substrate K,the second pathway is activated and culminates in the production of that pathway's end product Y.The activity of the first pathway is depressed simultaneously.What are the alternative substrates K and M acting like?

Doubling the concentration of enzyme will ______ the V_max and _____ the K_M.

The development of bacterial resistance to antibiotics is an example of what engine of evolution?

The effect of a competitive inhibitor can be reversed by _______.

What is the reason for treating a patient simultaneously with two antibiotics against the same bacterium?

Which property below is not a characteristic of enzymes?