Question 1

Which of the following events signals the termination of translation?

Accepted Answer

A) The ribosome reaches the end of the mRNA. 
B) The ribosome reaches a start codon. 
C) The ribosome reaches a stop codon. 
D) The ribosome runs out of charged tRNAs. 
E) The polypeptide chain folds into a protein. 
A) The ribosome reaches the end of the mRNA. 
B) The ribosome reaches a start codon. 
C) The ribosome reaches a stop codon. 
D) The ribosome runs out of charged tRNAs. 
E) The polypeptide chain folds into a protein.

Question 2

How are proteins sorted into their appropriate cell compartments in eukaryotes?

Accepted Answer

Proteins with specific "signal" sequence

Question 3

A new initiation event cannot occur on an mRNA molecule until the first ribosome falls away.

Accepted Answer

A) True 
 B)False

Question 4

In eukaryotes,the AUG initiation codon is located in the ________ sequence.

Accepted Answer

A) Shine-Dalgarno 
B) Kozak 
C) Khorana 
D) Goldberg-Hogness 
E) Pribnow 
A) Shine-Dalgarno 
B) Kozak 
C) Khorana 
D) Goldberg-Hogness 
E) Pribnow

Question 5

A peptide bond forms between the ________ of one amino acid and the ________ of another.

Accepted Answer

A) amino group,carboxyl group 
B) amino group,R group 
C) carboxyl group,sulfide group 
D) amino group,phosphate group 
E) R group,R group 
A) amino group,carboxyl group 
B) amino group,R group 
C) carboxyl group,sulfide group 
D) amino group,phosphate group 
E) R group,R group

Question 6

Which of the following is not a characteristic of proteins?

Accepted Answer

A) High molecular weight 
B) Presence of nitrogen 
C) Presence of amino acids 
D) Presence of nucleic acids 
E) Structure built of one or more polypeptides 
A) High molecular weight 
B) Presence of nitrogen 
C) Presence of amino acids 
D) Presence of nucleic acids 
E) Structure built of one or more polypeptides

Question 7

When does quaternary structure occur?

Accepted Answer

Quaternary structure occurs on

Question 8

How did von Ehrenstein et al.demonstrate that the specificity of codon recognition lies in the tRNA molecule and not in the amino acid it carries?

Accepted Answer

They chemically converted the cysteine o

Question 9

What is the wobble hypothesis,and what implications does it have for base-pairing rules and selective pressure on codons?

Accepted Answer

The wobble hypothesis refers to the dege

Question 10

In eukaryotes,the translation initiation complex forms in association with the 40S ribosomal subunit.

Accepted Answer

A) True 
 B)False

Question 11

Which of the following statements is correct?

Accepted Answer

A) For every codon,there is one amino acid. 
B) For every amino acid,there is one codon. 
C) A codon may signify more than one amino acid. 
D) Three codons make up an amino acid. 
E) Three amino acids make up a codon. 
A) For every codon,there is one amino acid. 
B) For every amino acid,there is one codon. 
C) A codon may signify more than one amino acid. 
D) Three codons make up an amino acid. 
E) Three amino acids make up a codon.

Question 12

Match between columns
                        Premises: Glycine
Arginine
Glutamic acid
Proline
Serine

Accepted Answer

The Answer of Neutral,nonpolar and Neutral,polar and Acidic and Basic is...

Question 13

A DNA codon reads GCC.Give the corresponding mRNA codon,tRNA anticodon,and amino acid.

Accepted Answer

mRNA codon: CGG; tRN

Question 14

Where does translation take place?

Accepted Answer

A) In the cytoplasm 
B) In the nucleus 
C) In the nucleolus 
D) Anywhere in the cell 
E) In the centriole 
A) In the cytoplasm 
B) In the nucleus 
C) In the nucleolus 
D) Anywhere in the cell 
E) In the centriole

Question 15

If a poly(C)is used as an mRNA and translated,a poly-glycine polypeptide is formed.If on the other hand a poly(G)mRNA is used,a poly-proline polypeptide is made.However,if both poly(C)and poly(G)are used in the same reaction,no polypeptide is made.Explain why.

Accepted Answer

Since mRNA is single stranded,

Question 16

Describe a cell-free protein synthesizing system with which you could determine unambiguously which codons specify which amino acids.

Accepted Answer

You could use a system with synthetic mR

Question 17

Molecules of mRNA are translated from 3' to 5',which is the opposite direction from which they were made.

Accepted Answer

A) True 
 B)False

Question 18

Every amino acid contains

Accepted Answer

A) an amino group and a hydroxyl group. 
B) an amino group and an acetyl group. 
C) a hydroxyl group and a carboxyl group. 
D) a carboxyl group and an amino group. 
E) a carboxyl group and a hydroxyl group. 
A) an amino group and a hydroxyl group. 
B) an amino group and an acetyl group. 
C) a hydroxyl group and a carboxyl group. 
D) a carboxyl group and an amino group. 
E) a carboxyl group and a hydroxyl group.

Question 19

If a tRNA anticodon reads GAI,to which mRNA codon(s)will it bind? What amino acid will the tRNA carry?

Accepted Answer

It will bind to CUU,

Question 20

In the experiments performed on bacteriophage T4 by Francis Crick and others,in which it was shown that the genetic code was triplet,what were the researchers trying to identify?

Accepted Answer

They were trying to identify r

Exam 6: Gene Expression: Translation

Which of the following events signals the termination of translation?

How are proteins sorted into their appropriate cell compartments in eukaryotes?

A new initiation event cannot occur on an mRNA molecule until the first ribosome falls away.

In eukaryotes,the AUG initiation codon is located in the ________ sequence.

A peptide bond forms between the ________ of one amino acid and the ________ of another.

Which of the following is not a characteristic of proteins?

When does quaternary structure occur?

How did von Ehrenstein et al.demonstrate that the specificity of codon recognition lies in the tRNA molecule and not in the amino acid it carries?

What is the wobble hypothesis,and what implications does it have for base-pairing rules and selective pressure on codons?

In eukaryotes,the translation initiation complex forms in association with the 40S ribosomal subunit.

Which of the following statements is correct?

A DNA codon reads GCC.Give the corresponding mRNA codon,tRNA anticodon,and amino acid.

Where does translation take place?

If a poly(C)is used as an mRNA and translated,a poly-glycine polypeptide is formed.If on the other hand a poly(G)mRNA is used,a poly-proline polypeptide is made.However,if both poly(C)and poly(G)are used in the same reaction,no polypeptide is made.Explain why.

Describe a cell-free protein synthesizing system with which you could determine unambiguously which codons specify which amino acids.

Molecules of mRNA are translated from 3' to 5',which is the opposite direction from which they were made.

Every amino acid contains

If a tRNA anticodon reads GAI,to which mRNA codon(s)will it bind? What amino acid will the tRNA carry?

In the experiments performed on bacteriophage T4 by Francis Crick and others,in which it was shown that the genetic code was triplet,what were the researchers trying to identify?

Genetics: An Introduction

DNA: The Genetic Material

DNA Replication

Gene Function

Gene Expression: Transcription

Dna Mutation, DNA Repair, and Transposable Elements

Genomics: The Mapping and Sequencing of Genomes

Functional and Comparative Genomics

Recombinant DNA Technology

Mendelian Genetics

Chromosomal Basis of Inheritance

Extensions of and Deviations From Mendelian Genetic Principles

Genetic Mapping in Eukaryotes

Genetics of Bacteria and Bacteriophages

Variations in Chromosome Structure and Number

Regulation of Gene Expression in Bacteria and Bacteriophages

Regulation of Gene Expression in Eukaryotes

Genetic Analysis of Development

Genetics of Cancer

Population Genetics

Quantitative Genetics

Molecular Evolution

Filters

A peptide bond forms between the of one amino acid and the of another.