Exam 10: Transmembrane Transport of Ions and Small Molecules

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ABC superfamily proteins are thought to act as ATP-dependent flippases in transporting:

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What evidence suggests that all of the P-class ion pumps evolved from a common ancestor even though they now transport different ions?

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How can a uniporter,GLUT2,be sufficient for entry of glucose from intestinal epithelial cells into the bloodstream?

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The partition coefficient K,the equilibrium constant for partitioning between oil and water,for butyric acid is about 10-²,and for 1,4-butanediol it is about 10-⁴.You add liposomes containing only water to a solution with an initial concentration of 1 mM butyric acid and 100 mM 1,4-butanediol outside the liposomes.What is the relative rate of diffusion of the two substances into the liposome interior?

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