Exam 5: Gene Expression and Gene Regulation

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The signal on the mRNA that causes translation to stop is the

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What treatments are available for patients with sickle-cell anemia? What is the first drug treatment that has been approved? What are some of the negatives of this drug? Why do you think that the use of this drug needs to be monitored by a doctor? If you suffered from sickle-cell anemia,would you want to take this drug? Explain your answers.

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How might a change in DNA nucleotide sequence of a gene cause a genetic disorder?

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Changing how tightly the DNA is wound does not affect gene expression.

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PROBLEM Consider a stretch of DNA (a hypothetical gene) that has the sequence TACGATAGTACCAGGATT on the strand that will be transcribed. -Now,our hypothetical gene has undergone a mutation.The mutant sequence is TACGATACTACCAGGATT.Transcribe the mutant sequence into mRNA,and determine the amino acid sequence of the resulting polypeptide chain.Determine if the nucleotide modification produced a different amino acid sequence n the protein.What do you think the consequence of this mutation would be in terms of protein function?

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MATCHING Match the term to the description. -mRNA

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Match the following descriptions with the appropriate letter. Match the following descriptions with the appropriate letter.    -these are different for different amino acids -these are different for different amino acids

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RNA polymerase makes mRNA from a DNA template.

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MATCHING Match the term to the description. -Ribosome

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A codon is

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What distinguishes amino acids from one another?

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In cystic fibrosis,the most common mutation produces a non-functional protein that controls the flow of chloride ions into and out of the cell.

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Gene regulation can be achieved by all of the following EXCEPT

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When genes are changed by mutations,this will never change the function of the proteins they encode.

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RNA polymerase is the enzyme that

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The region on the DNA where the RNA polymerase initially binds is called the

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Which of the following answers best describes the flow of information when a gene directs the synthesis of proteins?

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All of the following are functions of proteins EXCEPT

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An anticodon is

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Match the following descriptions with the appropriate letter. Match the following descriptions with the appropriate letter.    -carboxyl group -carboxyl group

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