Question 1

A Nobel Prize was not awarded for the discovery of the antipsychotic effects of chlorpromazine and the subsequent spark in psychopharmacology as a field likely due to…

Accepted Answer

A)  not having substantial impact on medicine. 
B)  the fact that other antipsychotic drugs were already in development. 
C)  heated disagreements about who was responsible for making the discovery. 
D)  a failure to treat schizophrenia in all patients. 
A)  not having substantial impact on medicine. 
B)  the fact that other antipsychotic drugs were already in development. 
C)  heated disagreements about who was responsible for making the discovery. 
D)  a failure to treat schizophrenia in all patients.

Question 2

Most evidence for a genetic basis of schizophrenia points to the…

Accepted Answer

A)  Finnish schizophrenia gene. 
B)  disrupted schizophrenia 1 gene. 
C)  dopamine transporter gene. 
D)  serotonin transporter gene. 
A)  Finnish schizophrenia gene. 
B)  disrupted schizophrenia 1 gene. 
C)  dopamine transporter gene. 
D)  serotonin transporter gene.

Question 3

A patient who displays mostly positive symptoms including suspiciousness would likely be identified as having…

Accepted Answer

A)  residual schizophrenia. 
B)  catatonic schizophrenia. 
C)  disorganized schizophrenia. 
D)  paranoid schizophrenia. 
A)  residual schizophrenia. 
B)  catatonic schizophrenia. 
C)  disorganized schizophrenia. 
D)  paranoid schizophrenia.

Question 4

How do antipsychotic drugs produce extrapyramidal side effects?

Accepted Answer

In schizophrenia,dopamine levels in the

Question 5

Describe the following adverse effects for antipsychotic drugs: extrapyramidal side effects,tardive dyskinesia,neuroleptic malignant syndrome,and hyperprolactinemia.

Accepted Answer

Extrapyramidal side effects consist of t

Question 6

While anticholinergic drugs reduce extrapyramidal side effects,they do not prevent the development of…

Accepted Answer

A)  cardiovascular dementia. 
B)  tardive dyskinesia. 
C)  acute dystonia. 
D)  extrapyramidal dyskinesia. 
A)  cardiovascular dementia. 
B)  tardive dyskinesia. 
C)  acute dystonia. 
D)  extrapyramidal dyskinesia.

Question 7

Catatonia will occur in some patients with the following disorders except…

Accepted Answer

A)  depression. 
B)  anxiety disorders. 
C)  alcohol withdrawal. 
D)  AIDS. 
A)  depression. 
B)  anxiety disorders. 
C)  alcohol withdrawal. 
D)  AIDS.

Question 8

The effective clinical dose of an antipsychotic drug…

Accepted Answer

A)  correlates with its binding affinity for NMDA receptors. 
B)  is not related to any known neurological actions. 
C)  is typically as effective as placebo. 
D)  correlates with its binding affinity for D₂ receptors. 
A)  correlates with its binding affinity for NMDA receptors. 
B)  is not related to any known neurological actions. 
C)  is typically as effective as placebo. 
D)  correlates with its binding affinity for D₂ receptors.

Question 9

In animals,if an experimental drug was shown to produce extrapyramidal side effects that subside as the drug's effects wear off,the researchers should conclude that the drug…

Accepted Answer

A)  will reduce positive symptoms in schizophrenia. 
B)  will produce Parkinson's disease. 
C)  acts on the primary motor cortex. 
D)  will worsen the symptoms of schizophrenia. 
A)  will reduce positive symptoms in schizophrenia. 
B)  will produce Parkinson's disease. 
C)  acts on the primary motor cortex. 
D)  will worsen the symptoms of schizophrenia.

Question 10

Chlorprozamine was developed as a(n)…

Accepted Answer

A)  antipsychotic drug. 
B)  antidepressant drugs. 
C)  preanesthetic drug. 
D)  analgesic drug. 
A)  antipsychotic drug. 
B)  antidepressant drugs. 
C)  preanesthetic drug. 
D)  analgesic drug.

Question 11

For identical twins,if one of the twins has schizophrenia,what is the chance that the other twin will have schizophrenia?

Accepted Answer

A)  0% 
B)  25% 
C)  50% 
D)  100% 
A)  0% 
B)  25% 
C)  50% 
D)  100%

Question 12

In schizophrenia,functional outcomes…

Accepted Answer

A)  are a patient's willingness to take antipsychotic medications. 
B)  consist of a patient's ability to separate reality from fantasy. 
C)  include a patient's self-reported number of hallucinations or other psychotic behaviors. 
D)  consist of the capabilities a patient has to perform normal everyday activities. 
A)  are a patient's willingness to take antipsychotic medications. 
B)  consist of a patient's ability to separate reality from fantasy. 
C)  include a patient's self-reported number of hallucinations or other psychotic behaviors. 
D)  consist of the capabilities a patient has to perform normal everyday activities.

Question 13

Chlorpromazine was developed specifically for the treatment of schizophrenia.

Accepted Answer

A) True 
 B)False

Question 14

Kraeplin used the term __________ for schizophrenia after noting certain changes in memory and thinking that he saw in elderly patients.

Accepted Answer

A)  split personality 
B)  hebephrenia praecox 
C)  dementia praecox 
D)  early-onset Alzheimer's disease 
A)  split personality 
B)  hebephrenia praecox 
C)  dementia praecox 
D)  early-onset Alzheimer's disease

Question 15

Hyperprolactinemia occurs from…

Accepted Answer

A)  agonism of D₁ receptors. 
B)  antagonism of D₂ receptors. 
C)  antagonism of 5-HT₂A receptors. 
D)  antagonism of NMDA receptors. 
A)  agonism of D₁ receptors. 
B)  antagonism of D₂ receptors. 
C)  antagonism of 5-HT₂A receptors. 
D)  antagonism of NMDA receptors.

Question 16

The first antipsychotic drugs,including chlorpromazine and haloperidol,are known by all of the following except…

Accepted Answer

A)  first-generation antipsychotics. 
B)  classical antipsychotics 
C)  neuroleptics. 
D)  early antipsychotics. 
A)  first-generation antipsychotics. 
B)  classical antipsychotics 
C)  neuroleptics. 
D)  early antipsychotics.

Question 17

The antimetic effects of antipsychotic drugs derive from…

Accepted Answer

A)  interrupted signalling from the chemoreceptor trigger zone to the area postrema. 
B)  blockade of dopamine receptors in the mesolimbic dopamine pathway. 
C)  antagonism of dopamien receptors in the hypothalamus. 
D)  activating pathways from the amygdala to the chemoreceptor trigger zone. 
A)  interrupted signalling from the chemoreceptor trigger zone to the area postrema. 
B)  blockade of dopamine receptors in the mesolimbic dopamine pathway. 
C)  antagonism of dopamien receptors in the hypothalamus. 
D)  activating pathways from the amygdala to the chemoreceptor trigger zone.

Question 18

Unlike the dopamine hypothesis,the glutamate hypothesis for schizophrenia…

Accepted Answer

A)  explains a lack of treatment response in some patients. 
B)  accounts for positive symptoms. 
C)  accounts for cognitive dysfunction. 
D)  explains drug withdrawal from antipsychotic medications. 
A)  explains a lack of treatment response in some patients. 
B)  accounts for positive symptoms. 
C)  accounts for cognitive dysfunction. 
D)  explains drug withdrawal from antipsychotic medications.

Question 19

When a typical antipsychotic drug is prescribed,physicians commonly also prescribe…

Accepted Answer

A)  a non-benzodiazepine hypnotic. 
B)  a benzodiazepine drug. 
C)  a psychostimulant drug. 
D)  an anticholinergic drug. 
A)  a non-benzodiazepine hypnotic. 
B)  a benzodiazepine drug. 
C)  a psychostimulant drug. 
D)  an anticholinergic drug.

Question 20

A patient with schizophrenia who has not improved after two attempts of treatment with an antipsycotic drug would be identified as…

Accepted Answer

A)  a poor antipsychotic metabolizer. 
B)  having treatment-resistant schizophrenia. 
C)  a patient with poor compliance. 
D)  having residual schizophrenia. 
A)  a poor antipsychotic metabolizer. 
B)  having treatment-resistant schizophrenia. 
C)  a patient with poor compliance. 
D)  having residual schizophrenia.

A Nobel Prize was not awarded for the discovery of the antipsychotic effects of chlorpromazine and the subsequent spark in psychopharmacology as a field likely due to…

Most evidence for a genetic basis of schizophrenia points to the…

A patient who displays mostly positive symptoms including suspiciousness would likely be identified as having…

How do antipsychotic drugs produce extrapyramidal side effects?

Describe the following adverse effects for antipsychotic drugs: extrapyramidal side effects,tardive dyskinesia,neuroleptic malignant syndrome,and hyperprolactinemia.

While anticholinergic drugs reduce extrapyramidal side effects,they do not prevent the development of…

Catatonia will occur in some patients with the following disorders except…

The effective clinical dose of an antipsychotic drug…

In animals,if an experimental drug was shown to produce extrapyramidal side effects that subside as the drug's effects wear off,the researchers should conclude that the drug…

Chlorprozamine was developed as a(n)…

For identical twins,if one of the twins has schizophrenia,what is the chance that the other twin will have schizophrenia?

In schizophrenia,functional outcomes…

Chlorpromazine was developed specifically for the treatment of schizophrenia.

Kraeplin used the term __________ for schizophrenia after noting certain changes in memory and thinking that he saw in elderly patients.

Hyperprolactinemia occurs from…

The first antipsychotic drugs,including chlorpromazine and haloperidol,are known by all of the following except…

The antimetic effects of antipsychotic drugs derive from…

Unlike the dopamine hypothesis,the glutamate hypothesis for schizophrenia…

When a typical antipsychotic drug is prescribed,physicians commonly also prescribe…

A patient with schizophrenia who has not improved after two attempts of treatment with an antipsycotic drug would be identified as…

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Filters

Exam 15: Antipsychotic Drugs

A Nobel Prize was not awarded for the discovery of the antipsychotic effects of chlorpromazine and the subsequent spark in psychopharmacology as a field likely due to…

Most evidence for a genetic basis of schizophrenia points to the…

A patient who displays mostly positive symptoms including suspiciousness would likely be identified as having…

How do antipsychotic drugs produce extrapyramidal side effects?

Describe the following adverse effects for antipsychotic drugs: extrapyramidal side effects,tardive dyskinesia,neuroleptic malignant syndrome,and hyperprolactinemia.

While anticholinergic drugs reduce extrapyramidal side effects,they do not prevent the development of…

Catatonia will occur in some patients with the following disorders except…

The effective clinical dose of an antipsychotic drug…

In animals,if an experimental drug was shown to produce extrapyramidal side effects that subside as the drug's effects wear off,the researchers should conclude that the drug…

Chlorprozamine was developed as a(n)…

For identical twins,if one of the twins has schizophrenia,what is the chance that the other twin will have schizophrenia?

In schizophrenia,functional outcomes…

Chlorpromazine was developed specifically for the treatment of schizophrenia.

Kraeplin used the term __________ for schizophrenia after noting certain changes in memory and thinking that he saw in elderly patients.

Hyperprolactinemia occurs from…

The first antipsychotic drugs,including chlorpromazine and haloperidol,are known by all of the following except…

The antimetic effects of antipsychotic drugs derive from…

Unlike the dopamine hypothesis,the glutamate hypothesis for schizophrenia…

When a typical antipsychotic drug is prescribed,physicians commonly also prescribe…

A patient with schizophrenia who has not improved after two attempts of treatment with an antipsycotic drug would be identified as…

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Filters