Question 1

A person who inherits the Le, Se, and H genes will have red cells that phenotype:

Accepted Answer

A)  Le(a+b+). 
B)  Le(a-b+). 
C)  Le(a-b-). 
D)  Le(a+b-). 
A)  Le(a+b+). 
B)  Le(a-b+). 
C)  Le(a-b-). 
D)  Le(a+b-). B

Question 2

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-Antigen of high incidence; antibody to it can cause severe transfusion reactions

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel J

Question 3

All the following statements are true regarding Lewis system antibodies except antibodies:

Accepted Answer

A)  may be observed at the immediate spin, 37° C, and antihuman globulin phases. 
B)  can be neutralized by Lewis substance. 
C)  may cause hemolysis in vitro. 
D)  do not react following enzyme treatment of cells. 
A)  may be observed at the immediate spin, 37° C, and antihuman globulin phases. 
B)  can be neutralized by Lewis substance. 
C)  may cause hemolysis in vitro. 
D)  do not react following enzyme treatment of cells. D

Question 4

If all red cells tested at room temperature are positive with a patient's serum except for cord cells, the probably antibody identity is:

Accepted Answer

A)  anti-Lu. 
B)  anti-Lea. 
C)  anti-I. 
D)  anti-M. 
A)  anti-Lu. 
B)  anti-Lea. 
C)  anti-I. 
D)  anti-M.

Question 5

The Donath-Landsteiner antibody is:

Accepted Answer

A)  an IgG auto anti-P. 
B)  an IgM auto anti-I. 
C)  anti-IH that reacts at cold temperatures. 
D)  IgG anti-pk. 
A)  an IgG auto anti-P. 
B)  an IgM auto anti-I. 
C)  anti-IH that reacts at cold temperatures. 
D)  IgG anti-pk.

Question 6

Antigens of the P system are structurally related to which of the following blood group systems?

Accepted Answer

A)  MNS 
B)  ABH 
C)  Kell 
D)  Duffy 
A)  MNS 
B)  ABH 
C)  Kell 
D)  Duffy

Question 7

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-System associated with chronic granulomatous disease

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 8

K1-positive donor red cells were mistakenly transfused to a recipient with anti-K. The patient's posttransfusion blood sample has a positive direct antiglobulin test with polyspecific antihuman globulin. The direct antiglobulin test is positive because anti-K is an __________ antibody that has sensitized the __________ cells in vivo.

Accepted Answer

A)  IgG, donor's 
B)  IgM, donor's 
C)  IgG, recipient's 
D)  IgM, recipient's 
A)  IgG, donor's 
B)  IgM, donor's 
C)  IgG, recipient's 
D)  IgM, recipient's

Question 9

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Accepted Answer

A)  the antigens are not fully developed at birth. 
B)  Lewis system antibodies do not cross the placenta. 
C)  the antibodies are not clinically significant. 
D)  all of the above are correct. 
A)  the antigens are not fully developed at birth. 
B)  Lewis system antibodies do not cross the placenta. 
C)  the antibodies are not clinically significant. 
D)  all of the above are correct.

Question 10

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-Antibody to this antigen demonstrates weak mixed field reactions

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 11

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-Antigens Yta and Ytb are in this system

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 12

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 13

Which of the following phenotypes is heterozygous?

Accepted Answer

A)  Fy(a-b+) 
B)  Jk(a+b-) 
C)  Fy(a+b+) 
D)  Le(a+b-) 
A)  Fy(a-b+) 
B)  Jk(a+b-) 
C)  Fy(a+b+) 
D)  Le(a+b-)

Question 14

Which of the following facts is not a characteristic of Kell system antibodies?

Accepted Answer

A)  Usually clinically significant IgG antibodies 
B)  Best detected in indirect antiglobulin test phases 
C)  Lose reactivity with proteolytic enzyme reagents 
D)  Do not bind complement proteins 
A)  Usually clinically significant IgG antibodies 
B)  Best detected in indirect antiglobulin test phases 
C)  Lose reactivity with proteolytic enzyme reagents 
D)  Do not bind complement proteins

Question 15

The following statements regarding anti-P1 are true except:

Accepted Answer

A)  anti-P1 will not react with enzyme-treated P1 positive red cells. 
B)  P2 individuals can make anti-P1. 
C)  anti-P1 is clinically not significant. 
D)  anti-P1 reacts best at room temperature. 
A)  anti-P1 will not react with enzyme-treated P1 positive red cells. 
B)  P2 individuals can make anti-P1. 
C)  anti-P1 is clinically not significant. 
D)  anti-P1 reacts best at room temperature.

Question 16

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-System associated with McLeod phenotype

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 17

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-Antigen has a higher frequency in females

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 18

Which condition is often associated with the presence of anti-I?

Accepted Answer

A)  Infectious mononucleosis 
B)  Mycoplasma pneumoniae infection 
C)  Pregnancy 
D)  Colon cancer 
A)  Infectious mononucleosis 
B)  Mycoplasma pneumoniae infection 
C)  Pregnancy 
D)  Colon cancer

Question 19

Match each characteristic with the appropriate blood group system. A selection may be used more than once.
-System associated with resistance to malaria

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Bg 
E) Xga
F)Sda antigen
G)Chido
H)Knops
I)Duffy
J)Vel

Question 20

Antibodies to Kidd, Kell, and Duffy blood group antigens share all the following characteristics except:

Accepted Answer

A)  can cause hemolytic disease of the newborn. 
B)  usually detected only by the indirect antiglobulin test. 
C)  enhanced with enzyme treatment. 
D)  can cause transfusion reactions. 
A)  can cause hemolytic disease of the newborn. 
B)  usually detected only by the indirect antiglobulin test. 
C)  enhanced with enzyme treatment. 
D)  can cause transfusion reactions.

A person who inherits the Le, Se, and H genes will have red cells that phenotype:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigen of high incidence; antibody to it can cause severe transfusion reactions

All the following statements are true regarding Lewis system antibodies except antibodies:

If all red cells tested at room temperature are positive with a patient's serum except for cord cells, the probably antibody identity is:

The Donath-Landsteiner antibody is:

Antigens of the P system are structurally related to which of the following blood group systems?

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with chronic granulomatous disease

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antibody to this antigen demonstrates weak mixed field reactions

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigens Yt^a and Yt^b are in this system

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Which of the following phenotypes is heterozygous?

Which of the following facts is not a characteristic of Kell system antibodies?

The following statements regarding anti-P₁ are true except:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with McLeod phenotype

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigen has a higher frequency in females

Which condition is often associated with the presence of anti-I?

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with resistance to malaria

Antibodies to Kidd, Kell, and Duffy blood group antigens share all the following characteristics except:

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Exam 6: Other Blood Group Systems

A person who inherits the Le, Se, and H genes will have red cells that phenotype:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigen of high incidence; antibody to it can cause severe transfusion reactions

All the following statements are true regarding Lewis system antibodies except antibodies:

If all red cells tested at room temperature are positive with a patient's serum except for cord cells, the probably antibody identity is:

The Donath-Landsteiner antibody is:

Antigens of the P system are structurally related to which of the following blood group systems?

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with chronic granulomatous disease

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antibody to this antigen demonstrates weak mixed field reactions

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigens Yta and Ytb are in this system

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Which of the following phenotypes is heterozygous?

Which of the following facts is not a characteristic of Kell system antibodies?

The following statements regarding anti-P1 are true except:

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with McLeod phenotype

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigen has a higher frequency in females

Which condition is often associated with the presence of anti-I?

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -System associated with resistance to malaria

Antibodies to Kidd, Kell, and Duffy blood group antigens share all the following characteristics except:

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Match each characteristic with the appropriate blood group system. A selection may be used more than once. -Antigens Yt^a and Yt^b are in this system

The following statements regarding anti-P₁ are true except: