Question 1

Cathelicidins perform which of the following functions? 
I. Chemotaxis
II. Neutralization of endotoxins
III. Broad spectrum antimicrobial activity

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III E

Question 2

Nitric oxide (NO) produced by phagocytes is cytotoxic to pathogens by inhibiting pathogen:
I- DNA synthesis
II- Mitochondrial respiration
III- Cell wall synthesis

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III C

Question 3

Which of the following are innate immune components that create a hostile environment for bacteria on the skin?

Accepted Answer

A)  Mucus and cilia 
B)  Bile salts and pH 
C)  Sweat and sebum 
D)  Normal flora and pH 
A)  Mucus and cilia 
B)  Bile salts and pH 
C)  Sweat and sebum 
D)  Normal flora and pH C

Question 4

Which are the molecules that are common to many pathogens and are recognized by phagocytes and other innate immune cells?

Accepted Answer

A)  PAMPs 
B)  Complement 
C)  Toll-like receptors 
D)  Mannose-binding lectin 
A)  PAMPs 
B)  Complement 
C)  Toll-like receptors 
D)  Mannose-binding lectin

Question 5

Where are antimicrobial cryptocidins produced?

Accepted Answer

A)  Skin 
B)  Liver 
C)  GI tract 
D)  Neutrophils 
A)  Skin 
B)  Liver 
C)  GI tract 
D)  Neutrophils

Question 6

The main immune component mediating septic shock is:

Accepted Answer

A)  TNF-a 
B)  Defensins 
C)  Complement 
D)  Interleukin-10 (IL-10) 
A)  TNF-a 
B)  Defensins 
C)  Complement 
D)  Interleukin-10 (IL-10)

Question 7

Which of the following acute phase reactants can reduce levels of nutritional iron available for bacterial uptake?
I. Haptoglobin
II. Ceruloplasmin
III. C-reactive protein (CRP)

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III

Question 8

Toll-like receptors (TLRs) activate the adaptive immune system by stimulating production of:

Accepted Answer

A)  Interleukin-1 (IL-1) 
B)  Interleukin-6 (IL-6) 
C)  Interleukin-12 (IL-12) 
D)  Tumor necrosis factor-alpha (TNF-a) 
A)  Interleukin-1 (IL-1) 
B)  Interleukin-6 (IL-6) 
C)  Interleukin-12 (IL-12) 
D)  Tumor necrosis factor-alpha (TNF-a)

Question 9

Binding of a pathogen to Toll-like receptors (TLRs) on phagocytes causes the release of cytokines that activate which type of adaptive immune cell?

Accepted Answer

A)  Mast cell 
B)  Neutrophil 
C)  Macrophage 
D)  Cytotoxic T cell 
A)  Mast cell 
B)  Neutrophil 
C)  Macrophage 
D)  Cytotoxic T cell

Question 10

Activation of a phagocyte by Toll-like receptors (TLRs) bound to a pathogen triggers what innate immune response?

Accepted Answer

A)  Phagocytosis 
B)  Complement activation 
C)  Cathelicidin production 
D)  Decrease in body temperature 
A)  Phagocytosis 
B)  Complement activation 
C)  Cathelicidin production 
D)  Decrease in body temperature

Cathelicidins perform which of the following functions? I. Chemotaxis II. Neutralization of endotoxins III. Broad spectrum antimicrobial activity

Nitric oxide (NO) produced by phagocytes is cytotoxic to pathogens by inhibiting pathogen: I- DNA synthesis II- Mitochondrial respiration III- Cell wall synthesis

Which of the following are innate immune components that create a hostile environment for bacteria on the skin?

Which are the molecules that are common to many pathogens and are recognized by phagocytes and other innate immune cells?

Where are antimicrobial cryptocidins produced?

The main immune component mediating septic shock is:

Which of the following acute phase reactants can reduce levels of nutritional iron available for bacterial uptake? I. Haptoglobin II. Ceruloplasmin III. C-reactive protein (CRP)

Toll-like receptors (TLRs) activate the adaptive immune system by stimulating production of:

Binding of a pathogen to Toll-like receptors (TLRs) on phagocytes causes the release of cytokines that activate which type of adaptive immune cell?

Activation of a phagocyte by Toll-like receptors (TLRs) bound to a pathogen triggers what innate immune response?

Cells and Organs of the Immune System

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters

Exam 2: Innate Immunity

Cathelicidins perform which of the following functions? I. Chemotaxis II. Neutralization of endotoxins III. Broad spectrum antimicrobial activity

Nitric oxide (NO) produced by phagocytes is cytotoxic to pathogens by inhibiting pathogen: I- DNA synthesis II- Mitochondrial respiration III- Cell wall synthesis

Which of the following are innate immune components that create a hostile environment for bacteria on the skin?

Which are the molecules that are common to many pathogens and are recognized by phagocytes and other innate immune cells?

Where are antimicrobial cryptocidins produced?

The main immune component mediating septic shock is:

Which of the following acute phase reactants can reduce levels of nutritional iron available for bacterial uptake? I. Haptoglobin II. Ceruloplasmin III. C-reactive protein (CRP)

Toll-like receptors (TLRs) activate the adaptive immune system by stimulating production of:

Binding of a pathogen to Toll-like receptors (TLRs) on phagocytes causes the release of cytokines that activate which type of adaptive immune cell?

Activation of a phagocyte by Toll-like receptors (TLRs) bound to a pathogen triggers what innate immune response?

Cells and Organs of the Immune System

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters