Exam 4: Pharmacodynamics

Mr. Woodward takes two drugs at the same time. His physician determines that if the two agents interact with each other, they may produce additive ____ responses to each other.

Mr. Woodward takes another drug that results in a very uncomfortable immune-mediated response by his body against the drug. It does not seem related to dose. Mr. Woodward has experienced a(n):

After her patient receives a new drug, Dr. Anderson monitors the patient to determine the amount that reaches and remains in the systemic circulation. To determine this accurately, Dr. Anderson would most likely want to monitor the rate and extent of:

Mr. Woodward takes an antihistamine and reports that it also has a mild, calming effect on him. His physician tells him that this is not at all unusual. The antianxiety effect of this drug is called a(n):

To discover the plasma concentrations that produce the desired drug effect without toxicity means to establish the drug's:

Mrs. Jennings takes a new medication, in addition to several she has used for years. The new agent is fairly effective, but it seems to interfere with the action of an older drug that normally has greater efficacy. Mrs. Jennings' new drug is apparently acting as a:

LD50 represents:

If a researcher is looking for the highest plasma concentration attained from a dose of a specific drug, he or she would be looking for its:

Mr. Clemmens receives a combination of drugs from several different physicians. His newest drug inactivates the receptor so that its agonist cannot be effective, no matter how much the physician is able to increase the agonist's concentration. The newest drug in Mr. Clemmens' regimen is a:

Drug X has a strong affinity for a specific receptor, and this enables it to elicit a(n) ____ effect.

Mrs. Jennings' physician is monitoring how long it takes after she administers her medication until she sees or feels the first sign of its effect. The physician is obviously concerned with the drug's:

The degree to which a drug is able to produce its desired effect is its:

Mrs. Peters suffers an acute bronchospasm and receives epinephrine. This drug enhances the normal physiologic function of its beta-2 receptor to stimulate bronchodilation. No new function was developed as a result. Mrs. Peters' epinephrine has a(n) ____ effect.

A laboratory is testing the relative safety of a drug, producing a ratio that is very close to 1. This calculation suggests that:

Mrs. Jennings is switched to a drug that resembles the ____ to which an enzyme attaches, resulting in a drug-enzyme interaction.