Question 1

Which of the following drugs is used to treat rheumatoid arthritis?

Accepted Answer

A) Tolcapone 
B) Etanercept 
C) Topiramate 
D) Risdronate. 
A) Tolcapone 
B) Etanercept 
C) Topiramate 
D) Risdronate.

Question 2

Repaglinide is a(n) ____________ used to treat __________ and rarely has the adverse effect of inducing ____________.

Accepted Answer

A) Non-selective beta-blocker, hypotension, tachycardia. 
B) Hypoglycemic, diabetes, hypoglycemia. 
C) Anti-psychotic, schizophrenia, psychotic breaks. 
D) Platelet inhibitor, post-MI, bleeding. 
A) Non-selective beta-blocker, hypotension, tachycardia. 
B) Hypoglycemic, diabetes, hypoglycemia. 
C) Anti-psychotic, schizophrenia, psychotic breaks. 
D) Platelet inhibitor, post-MI, bleeding.

Question 3

Which of the following statements is false concerning Phase I, II or III clinical trials?

Accepted Answer

A) A phase I trial is often quite large (N>500) and seeks to determine the safe dose range for a new drug. 
B) A phase II trial is often larger than a phase I trial and seeks to determine if a new drug is effective enough to test in a phase III trial and to delineate adverse effects. 
C) A Phase III trial compares a new treatment with an established treatment and is usually much larger than either a phase I or a phase II trial. 
D) All three of the statements are correct. 
A) A phase I trial is often quite large (N>500) and seeks to determine the safe dose range for a new drug. 
B) A phase II trial is often larger than a phase I trial and seeks to determine if a new drug is effective enough to test in a phase III trial and to delineate adverse effects. 
C) A Phase III trial compares a new treatment with an established treatment and is usually much larger than either a phase I or a phase II trial. 
D) All three of the statements are correct.

Question 4

Of the following methods of administration, which is the best advice for a patient taking a bisphosphonate?

Accepted Answer

A) Take with as small amount of food or water as possible. 
B) Take in the morning at least 30 minutes before any meal. Drink a full glass of water with the bisphosphonate. 
C) Take anytime during the day when convenient. 
D) Bisphosphonates should be taken at night to minimize gastric upset. 
A) Take with as small amount of food or water as possible. 
B) Take in the morning at least 30 minutes before any meal. Drink a full glass of water with the bisphosphonate. 
C) Take anytime during the day when convenient. 
D) Bisphosphonates should be taken at night to minimize gastric upset.

Question 5

Which of the following statements is true concerning SERMs (selective estrogen receptor modulators)?
I. When using a SERM like tamoxifen, bone pain may be indicative of a good therapeutic response.
II. Individuals on SERMs may experience hot flashes.
III. Patients on SERMs must be monitored for possible thromboembolic events.
IV. At this point, it appears that all SERMs reduce the risk of breast cancer.

Accepted Answer

A) I only 
B) I and II only 
C) II and IV only 
D) All are true statments. 
A) I only 
B) I and II only 
C) II and IV only 
D) All are true statments.

Question 6

For the following chemotherapeutic agents, determine the INCORRECT combination of agent/mechanism of action.
I. Olanzapine/ Dopamine and Serotonin-2 receptor antagonist
II. Paclitaxel/anti-mitotic
III. Pindolol/ beta-adrenergic antagonist
IV. Donepezil/alkylating agent

Accepted Answer

A) I and II only 
B) II and IV only 
C) III and IV only 
D) IV only 
A) I and II only 
B) II and IV only 
C) III and IV only 
D) IV only

Question 7

Which of the following class of drugs is used as anti-emetics?

Accepted Answer

A) Fluroquinolones 
B) MAO Inhibitors 
C) 5HT-3 receptor antagonists 
D) HMG-CoA reductase inhibitors. 
A) Fluroquinolones 
B) MAO Inhibitors 
C) 5HT-3 receptor antagonists 
D) HMG-CoA reductase inhibitors.

Question 8

A patient has a Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency. Of the following drugs, which should be avoided in this patient?

Accepted Answer

A) Macrolides 
B) Omeprazole 
C) Vitamin B12 
D) Quinolones 
A) Macrolides 
B) Omeprazole 
C) Vitamin B12 
D) Quinolones

Question 9

A patient is diagnosed with iron-deficiency anemia and is give iron supplements. They ask if they should take it with food. Your response is:

Accepted Answer

A) Iron is best absorbed when taken with milk. 
B) Iron should be taken with food to increase absorption and minimize gastric upset. 
C) Iron is best taken with water only and at least one hour before eating. 
D) None of the above is correct. 
A) Iron is best absorbed when taken with milk. 
B) Iron should be taken with food to increase absorption and minimize gastric upset. 
C) Iron is best taken with water only and at least one hour before eating. 
D) None of the above is correct.

Question 10

In which of the following is the brand name for an inhalation form of insulin?

Accepted Answer

A) Exubera 
B) Humulin 
C) NovoLog 
D) Lantus 
A) Exubera 
B) Humulin 
C) NovoLog 
D) Lantus

Question 11

What do the "B" and the "M" in the chemotherapeutic combination BEAM represent?

Accepted Answer

A) BCNU (carmustine) and melphalan 
B) Bendamustine and melphalan 
C) BCNU (carmustine) and meloxicam 
D) Bleomycin and Matulane (procarbazine) 
A) BCNU (carmustine) and melphalan 
B) Bendamustine and melphalan 
C) BCNU (carmustine) and meloxicam 
D) Bleomycin and Matulane (procarbazine)

Question 12

Which of the following is the brand name for hydrocortisone?
I. Remicade
II. Cortef
III. Locoid
IV. Westcort

Accepted Answer

A) I and II only 
B) II and IV only 
C) II, III and IV only 
D) I and IV only 
A) I and II only 
B) II and IV only 
C) II, III and IV only 
D) I and IV only

Question 13

What might nizatidine (Axid) be prescribed for?
I. Situational depression
II. Active duodenal ulcer
III. Mild seasonal affective disorder (SAD)
IV. Gastroesophageal reflux disease (GERD)

Accepted Answer

A) I and III only 
B) II and IV only 
C) All of the above 
D) None of the above 
A) I and III only 
B) II and IV only 
C) All of the above 
D) None of the above

Question 14

Which of the following drugs are bronchodilators and used to treat asthma?
I. Albuterol
II. Isoproterenol
III. Terbutaline
IV. Mirtazapine

Accepted Answer

A) All of the above 
B) None of the above 
C) I, II and III only 
D) I and II only 
A) All of the above 
B) None of the above 
C) I, II and III only 
D) I and II only

Question 15

A 28-year-old female patient is diagnosed with Graves' disease. She is placed on liothyronine. Why is that inappropriate?

Accepted Answer

A) Liothyronine is synthetic T3. Graves' disease is a state of hyperthyroidism, and Liothyronine is contraindicated.. 
B) It is not inappropriate; use of liothyronine follows current practice guidelines. 
C) She should be given Levothyroxine instead; the Levothyroxine will be converted in vivo to T3. 
D) Liothyronine is a Category X drug and should not be given to females of child bearing age. 
A) Liothyronine is synthetic T3. Graves' disease is a state of hyperthyroidism, and Liothyronine is contraindicated.. 
B) It is not inappropriate; use of liothyronine follows current practice guidelines. 
C) She should be given Levothyroxine instead; the Levothyroxine will be converted in vivo to T3. 
D) Liothyronine is a Category X drug and should not be given to females of child bearing age.

Question 16

What is prazosin used to treat?

Accepted Answer

A) Grave's disease. 
B) Hypertension 
C) Hypercholesterolemia 
D) Homocyteinemia 
A) Grave's disease. 
B) Hypertension 
C) Hypercholesterolemia 
D) Homocyteinemia

Question 17

Which of the following is galantamine used to treat?
I. Seizures
II. Myocarditis
III. Alzheimer's disease
IV. Mild cognitive dysfunction

Accepted Answer

A) I only 
B) II only 
C) III only 
D) All of the above 
A) I only 
B) II only 
C) III only 
D) All of the above

Question 18

Eletriptan (Relpax) is used to treat _______, and it is contraindicated with/in ___________. Its major adverse reaction is _______________.

Accepted Answer

A) Gout, blood dyscrasias, arrhythmias 
B) Rheumatoid arthritis, osteoporosis, spontaneous fractures. 
C) Diabetes, hypoglycemia, respiratory arrest 
D) Migraine (with or without aura), uncontrolled hypertension, ischemia 
A) Gout, blood dyscrasias, arrhythmias 
B) Rheumatoid arthritis, osteoporosis, spontaneous fractures. 
C) Diabetes, hypoglycemia, respiratory arrest 
D) Migraine (with or without aura), uncontrolled hypertension, ischemia

Question 19

A patient is on simvastatin. What is the biochemical pathway that is inhibited by this drug?

Accepted Answer

A) The pentose phosphate pathway 
B) The mevalonate pathway 
C) The eiconosoid pathway 
D) The electron transport chain 
A) The pentose phosphate pathway 
B) The mevalonate pathway 
C) The eiconosoid pathway 
D) The electron transport chain

Question 20

A clinical trial is studying the response of 2 independent groups. If numeric scales are used, which of the following would be the preferred mode of statistical analysis?

Accepted Answer

A) ANOVA 
B) Paired t-tests 
C) Mann-Whitney 
D) Chi-square 
A) ANOVA 
B) Paired t-tests 
C) Mann-Whitney 
D) Chi-square

Which of the following drugs is used to treat rheumatoid arthritis?

Repaglinide is a(n) used to treat and rarely has the adverse effect of inducing __.

Which of the following statements is false concerning Phase I, II or III clinical trials?

Of the following methods of administration, which is the best advice for a patient taking a bisphosphonate?

For the following chemotherapeutic agents, determine the INCORRECT combination of agent/mechanism of action. I. Olanzapine/ Dopamine and Serotonin-2 receptor antagonist II. Paclitaxel/anti-mitotic III. Pindolol/ beta-adrenergic antagonist IV. Donepezil/alkylating agent

Which of the following class of drugs is used as anti-emetics?

A patient has a Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency. Of the following drugs, which should be avoided in this patient?

A patient is diagnosed with iron-deficiency anemia and is give iron supplements. They ask if they should take it with food. Your response is:

In which of the following is the brand name for an inhalation form of insulin?

What do the "B" and the "M" in the chemotherapeutic combination BEAM represent?

Which of the following is the brand name for hydrocortisone? I. Remicade II. Cortef III. Locoid IV. Westcort

What might nizatidine (Axid) be prescribed for? I. Situational depression II. Active duodenal ulcer III. Mild seasonal affective disorder (SAD) IV. Gastroesophageal reflux disease (GERD)

Which of the following drugs are bronchodilators and used to treat asthma? I. Albuterol II. Isoproterenol III. Terbutaline IV. Mirtazapine

A 28-year-old female patient is diagnosed with Graves' disease. She is placed on liothyronine. Why is that inappropriate?

What is prazosin used to treat?

Which of the following is galantamine used to treat? I. Seizures II. Myocarditis III. Alzheimer's disease IV. Mild cognitive dysfunction

Eletriptan (Relpax) is used to treat _, and it is contraindicated with/in _. Its major adverse reaction is ___________.

A patient is on simvastatin. What is the biochemical pathway that is inhibited by this drug?

A clinical trial is studying the response of 2 independent groups. If numeric scales are used, which of the following would be the preferred mode of statistical analysis?

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Exam 5: Pharmacological

Which of the following drugs is used to treat rheumatoid arthritis?

Repaglinide is a(n) ____________ used to treat __________ and rarely has the adverse effect of inducing ____________.

Which of the following statements is false concerning Phase I, II or III clinical trials?

Of the following methods of administration, which is the best advice for a patient taking a bisphosphonate?

For the following chemotherapeutic agents, determine the INCORRECT combination of agent/mechanism of action. I. Olanzapine/ Dopamine and Serotonin-2 receptor antagonist II. Paclitaxel/anti-mitotic III. Pindolol/ beta-adrenergic antagonist IV. Donepezil/alkylating agent

Which of the following class of drugs is used as anti-emetics?

A patient has a Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency. Of the following drugs, which should be avoided in this patient?

A patient is diagnosed with iron-deficiency anemia and is give iron supplements. They ask if they should take it with food. Your response is:

In which of the following is the brand name for an inhalation form of insulin?

What do the "B" and the "M" in the chemotherapeutic combination BEAM represent?

Which of the following is the brand name for hydrocortisone? I. Remicade II. Cortef III. Locoid IV. Westcort

What might nizatidine (Axid) be prescribed for? I. Situational depression II. Active duodenal ulcer III. Mild seasonal affective disorder (SAD) IV. Gastroesophageal reflux disease (GERD)

Which of the following drugs are bronchodilators and used to treat asthma? I. Albuterol II. Isoproterenol III. Terbutaline IV. Mirtazapine

A 28-year-old female patient is diagnosed with Graves' disease. She is placed on liothyronine. Why is that inappropriate?

What is prazosin used to treat?

Which of the following is galantamine used to treat? I. Seizures II. Myocarditis III. Alzheimer's disease IV. Mild cognitive dysfunction

Eletriptan (Relpax) is used to treat _______, and it is contraindicated with/in ___________. Its major adverse reaction is _______________.

A patient is on simvastatin. What is the biochemical pathway that is inhibited by this drug?

A clinical trial is studying the response of 2 independent groups. If numeric scales are used, which of the following would be the preferred mode of statistical analysis?

Administrative

Medication Aide Certification Exam

Physician Assistants

Process Dispense

Filters

Repaglinide is a(n) used to treat and rarely has the adverse effect of inducing __.

Eletriptan (Relpax) is used to treat _, and it is contraindicated with/in _. Its major adverse reaction is ___________.