Exam 1: Vesiculobullous Diseases

A 76-year-old woman presents with multiple painful oral ulcers that have been persistent for at least 3 months. She states that the ulcers are preceded by blisters. She recently developed an ocular irritation that she described as a gritty sensation when she closes her eyes. Other than her chief complaint and hypertension, she is in good health. She most likely has which of the following?

Herpes whitlow is now rarely seen in dental practitioners because:

A positive Nikolsky sign may be evident in which of the following conditions?

Which of the following herpesviruses is most frequently the cause of recurrent oral and perioral vesicular eruptions?

Secondary varicella-zoster virus infections:

Direct immunofluorescence is a laboratory test that is effective in confirming which of the following?

Corticosteroids are the drugs of choice for the treatment of all the following except:

Biopsy confirmation of mucous membrane pemphigoid can be made by which of the following?

Systemic corticosteroids can affect many metabolic processes. Which of the following effects of prednisone is regarded as therapeutic when prescribed for patients with pemphigus vulgaris and mucous membrane pemphigoid?

A patient with a secondary oral herpes simplex infection would:

Keratinocyte dysadhesion, also known as acantholysis, due to desmosome weakening by autoantibodies is the disease mechanism attributed to which of the following?

The Tzanck cells in pemphigus vulgaris result from:

Which of the following frequently appears in the mouth before expressing itself in the skin?

Which of the following conditions exhibits subepithelial separation microscopically?

Eye lesions may occur with which of the following conditions?

Systemic corticosteroids, when used at relatively high doses and for extended periods, may induce all the following side effects except:

Herpes simplex virus may cause vesiculoulcerative lesions on any mucosal surface in all the following patients except _____ patients.

Risk of transmission of herpes simplex infection is greatest in which of the following clinical stages?

Intercellular deposits of IgG are consistently found in oral epithelium in which of the following?

Which of the following vesiculobullous diseases occurs because of attachment of autoantibodies to antigens (desmoglein 3) in keratinocyte desmosomes?