Question 1

What is the term for transcription factors that decrease transcriptional activity?

Accepted Answer

A) deregulators 
B) depleters 
C) regulators 
D) repressors 
E) TBPs 
A) deregulators 
B) depleters 
C) regulators 
D) repressors 
E) TBPs

Question 2

The action of which small RNA inhibits the movement of transposable elements?

Accepted Answer

A) miRNA 
B) siRNA 
C) piRNA 
D) tRNA 
A) miRNA 
B) siRNA 
C) piRNA 
D) tRNA

Question 3

Which is a type of DNA-binding domain found in transcription factors?

Accepted Answer

A) TAF 
B) zinc finger 
C) major groove 
D) leucine zipper 
E) corepressor 
A) TAF 
B) zinc finger 
C) major groove 
D) leucine zipper 
E) corepressor

Question 4

How can one primary mRNA result in several polypeptides with different amino acid sequences?

Accepted Answer

A) alternative splicing of exons 
B) phosphorylation of proteins after translation 
C) incorporation of an amino acid at a stop codon 
D) addition of a poly-A tail to the mRNA 
A) alternative splicing of exons 
B) phosphorylation of proteins after translation 
C) incorporation of an amino acid at a stop codon 
D) addition of a poly-A tail to the mRNA

Question 5

Where do mutations that alter the amount of protein synthesized from a reporter construct occur most often?

Accepted Answer

A) the reporter gene 
B) cis-acting DNA elements 
C) X-gal coding sequence 
D) RNA polymerase II gene 
E) None of the choices is correct. 
A) the reporter gene 
B) cis-acting DNA elements 
C) X-gal coding sequence 
D) RNA polymerase II gene 
E) None of the choices is correct.

Question 6

Which of these types of gene regulation occurs earliest in the process of gene expression?

Accepted Answer

A) alternative splicing 
B) protein modification 
C) export of mRNA to the cytoplasm 
D) translation initiation 
A) alternative splicing 
B) protein modification 
C) export of mRNA to the cytoplasm 
D) translation initiation

Question 7

What is the name of the cis-acting DNA sequence at which the transcriptional initiation complex forms?

Accepted Answer

A) promoter 
B) terminator 
C) enhancer 
D) activator 
E) transcription factor 
A) promoter 
B) terminator 
C) enhancer 
D) activator 
E) transcription factor

Question 8

Which could be accomplished using ribosome profiling?

Accepted Answer

A) identifying enhancers that activate genes in muscle tissue 
B) identifying all of the genes regulated by a particular transcription factor 
C) quantifying the level at which the mRNAs in a cell are being translated 
D) calculating the location and number of genes in a genome 
A) identifying enhancers that activate genes in muscle tissue 
B) identifying all of the genes regulated by a particular transcription factor 
C) quantifying the level at which the mRNAs in a cell are being translated 
D) calculating the location and number of genes in a genome

Question 9

What is a transcription factor that associates with an enhancer and causes an increase in initiation of transcription?

Accepted Answer

A) initiator 
B) activator 
C) repressor 
D) enhancer 
E) demethylase 
A) initiator 
B) activator 
C) repressor 
D) enhancer 
E) demethylase

Question 10

A protein with a zinc-finger domain most likely has what type of activity?

Accepted Answer

A) modifying proteins with phosphate groups 
B) DNA binding 
C) mRNA splicing 
D) initiation of translation 
A) modifying proteins with phosphate groups 
B) DNA binding 
C) mRNA splicing 
D) initiation of translation

Question 11

What describes a situation in which an allele's expression depends on the parent from which it was inherited?

Accepted Answer

A) genomic imprinting 
B) x chromosome inactivation 
C) mosaicism 
D) homodimerization 
E) x-linkage 
A) genomic imprinting 
B) x chromosome inactivation 
C) mosaicism 
D) homodimerization 
E) x-linkage

Question 12

A trans-acting factor functions by

Accepted Answer

A) binding to enhancers or promoters leading to increased or decreased transcription. 
B) regulating the expression of the gene from which it was transcribed. 
C) transporting mRNAs from the nucleus to the cytoplasm. 
D) binding to and increasing the activity of DNA polymerase. 
E) binding only to promoters and increasing the binding of RNA polymerase. 
A) binding to enhancers or promoters leading to increased or decreased transcription. 
B) regulating the expression of the gene from which it was transcribed. 
C) transporting mRNAs from the nucleus to the cytoplasm. 
D) binding to and increasing the activity of DNA polymerase. 
E) binding only to promoters and increasing the binding of RNA polymerase.

Question 13

DNA sequences that are binding sites for transcription factors are called

Accepted Answer

A) cross-reacting. 
B) cis-acting elements. 
C) trans-acting factors. 
D) origins of transcription. 
E) transcription factors. 
A) cross-reacting. 
B) cis-acting elements. 
C) trans-acting factors. 
D) origins of transcription. 
E) transcription factors.

Question 14

The enhancer shown in the diagram is able to regulate transcription of which genes?   (Select all that apply. )

Accepted Answer

A) Gene A 
B) Gene B 
C) Gene C 
D) Gene D 
A) Gene A 
B) Gene B 
C) Gene C 
D) Gene D

Question 15

In Drosophila females, Sxl protein directly alters the splicing pattern of the transcripts from which gene(s)? (Select all that apply. )

Accepted Answer

A) yp1 
B) fru 
C) Sxl 
D) Tra 
E) Dsx 
A) yp1 
B) fru 
C) Sxl 
D) Tra 
E) Dsx

Question 16

What is the primary function of basal transcription factors?

Accepted Answer

A) repress transcription initiation of specific genes 
B) assist RNA polymerase binding to the promoter 
C) increase transcription by binding enhancer sequences 
D) bind to activators or repressors and modify histone tails 
E) add poly-A to the 3′ end of transcripts 
A) repress transcription initiation of specific genes 
B) assist RNA polymerase binding to the promoter 
C) increase transcription by binding enhancer sequences 
D) bind to activators or repressors and modify histone tails 
E) add poly-A to the 3′ end of transcripts

What is the term for transcription factors that decrease transcriptional activity?

The action of which small RNA inhibits the movement of transposable elements?

Which is a type of DNA-binding domain found in transcription factors?

How can one primary mRNA result in several polypeptides with different amino acid sequences?

Where do mutations that alter the amount of protein synthesized from a reporter construct occur most often?

Which of these types of gene regulation occurs earliest in the process of gene expression?

What is the name of the cis-acting DNA sequence at which the transcriptional initiation complex forms?

Which could be accomplished using ribosome profiling?

What is a transcription factor that associates with an enhancer and causes an increase in initiation of transcription?

A protein with a zinc-finger domain most likely has what type of activity?

What describes a situation in which an allele's expression depends on the parent from which it was inherited?

A trans-acting factor functions by

DNA sequences that are binding sites for transcription factors are called

The enhancer shown in the diagram is able to regulate transcription of which genes? (Select all that apply. )

In Drosophila females, Sxl protein directly alters the splicing pattern of the transcripts from which gene(s)? (Select all that apply. )

What is the primary function of basal transcription factors?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Exam 17: Gene Regulation in Eukaryotes

What is the term for transcription factors that decrease transcriptional activity?

The action of which small RNA inhibits the movement of transposable elements?

Which is a type of DNA-binding domain found in transcription factors?

How can one primary mRNA result in several polypeptides with different amino acid sequences?

Where do mutations that alter the amount of protein synthesized from a reporter construct occur most often?

Which of these types of gene regulation occurs earliest in the process of gene expression?

What is the name of the cis-acting DNA sequence at which the transcriptional initiation complex forms?

Which could be accomplished using ribosome profiling?

What is a transcription factor that associates with an enhancer and causes an increase in initiation of transcription?

A protein with a zinc-finger domain most likely has what type of activity?

What describes a situation in which an allele's expression depends on the parent from which it was inherited?

A trans-acting factor functions by

DNA sequences that are binding sites for transcription factors are called

The enhancer shown in the diagram is able to regulate transcription of which genes? (Select all that apply. )

In Drosophila females, Sxl protein directly alters the splicing pattern of the transcripts from which gene(s)? (Select all that apply. )

What is the primary function of basal transcription factors?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters