Question 1

_____ express FcεRI and contain granules containing inflammatory mediators.(Select all that apply.)

Accepted Answer

A) macrophages 
B) activated eosinophils 
C) mast cells 
D) natural killer cells 
E) basophils. 
A) macrophages 
B) activated eosinophils 
C) mast cells 
D) natural killer cells 
E) basophils.

Question 2

Which of the following are associated with soluble antigen? (Select all that apply.)

Accepted Answer

A) type I hypersensitivity 
B) type II hypersensitivity 
C) type III hypersensitivity 
D) type IV hypersensitivity 
E) mast-cell activation. 
A) type I hypersensitivity 
B) type II hypersensitivity 
C) type III hypersensitivity 
D) type IV hypersensitivity 
E) mast-cell activation.

Question 3

Which of the following is not mediated by antibodies?

Accepted Answer

A) type I hypersensitivity 
B) type II hypersensitivity 
C) type III hypersensitivity 
D) type IV hypersensitivity. 
A) type I hypersensitivity 
B) type II hypersensitivity 
C) type III hypersensitivity 
D) type IV hypersensitivity.

Question 4

Which of the following genetic polymorphisms is associated with a predisposition to asthma? (Select all that apply.)

Accepted Answer

A) promoter variants of IL-5 
B) structural variant of IgG receptor 
C) HLA class II allotypes 
D) β2-adrenergic receptor variant 
E) ACOX5 (5-lipoxygenase). 
A) promoter variants of IL-5 
B) structural variant of IgG receptor 
C) HLA class II allotypes 
D) β2-adrenergic receptor variant 
E) ACOX5 (5-lipoxygenase).

Question 5

Identify four different ways in which an individual may come into contact with an allergen and provide two examples of allergens for each type of contact.

Accepted Answer

(i)Inhalation: house dust mite feces,ani

Question 6

All of the following are released immediately by mast cells after FcεRI cross-linking except _____.

Accepted Answer

A) heparin 
B) eicosanoids 
C) neutral proteases 
D) histamine 
E) TNF-α. 
A) heparin 
B) eicosanoids 
C) neutral proteases 
D) histamine 
E) TNF-α.

Question 7

Match between columns
                        Premises: wheezing
diarrhea
vomiting
decrease in blood pressure
swelling of tissues
violent bursts of sneezing
constriction of the throat

Accepted Answer

The Answer of gastrointestinal tract and respiratory tract and heart is...

Question 8

Which of the following allergens is not likely to be encountered through inhalation?

Accepted Answer

A) plant pollen 
B) metals 
C) animal dander 
D) mold spores 
E) house dust mite feces. 
A) plant pollen 
B) metals 
C) animal dander 
D) mold spores 
E) house dust mite feces.

Question 9

Which of the following are matched correctly? (Select all that apply.)

Accepted Answer

A) type I hypersensitivity: IgE 
B) type II hypersensitivity: IgG 
C) type III hypersensitivity: immune complexes 
D) type IV hypersensitivity: IgG 
E) type IV hypersensitivity: delayed-type hypersensitivity. 
A) type I hypersensitivity: IgE 
B) type II hypersensitivity: IgG 
C) type III hypersensitivity: immune complexes 
D) type IV hypersensitivity: IgG 
E) type IV hypersensitivity: delayed-type hypersensitivity.

Question 10

What are the effects of histamine binding to the H1 receptor on smooth muscle,mucosal epithelia,and the endothelial cells of blood vessels.

Accepted Answer

When smooth muscle cells bind histamine

Question 11

Some allergies can be treated by a procedure called desensitization.
A.Explain two current approaches to desensitization.
B.Explain the main disadvantage associated with each.

Accepted Answer

A. (i)One approach to desensitization is

Question 12

The wheal-and-flare inflammatory reaction is an example of

Accepted Answer

A) an immediate type I allergic response 
B) a late-phase type I allergic response 
C) a late-phase type IV allergic response 
D) an immediate type III allergic response 
E) a late-phase type III allergic response. 
A) an immediate type I allergic response 
B) a late-phase type I allergic response 
C) a late-phase type IV allergic response 
D) an immediate type III allergic response 
E) a late-phase type III allergic response.

Question 13

Match between columns
                        Premises: allergen
immediate hypersensitivity
hygiene hypothesis
delayed-type hypersensitivity
allergy

Accepted Answer

The Answer of type IV hypersensitivity and epidemic of allergy is...

Question 14

A.Explain why it is essential that FcεRI and Fcε RII are not able to bind simultaneously to the same IgE molecule.
B.Why does simultaneous binding not occur?

Accepted Answer

A.Armed mast cells and basophils become

Question 15

Which of the following is associated with type III hypersensitivity?

Accepted Answer

A) nickel 
B) recombinant human insulin 
C) plant oil 
D) mouse-derived monoclonal antibody 
E) helminth infection. 
A) nickel 
B) recombinant human insulin 
C) plant oil 
D) mouse-derived monoclonal antibody 
E) helminth infection.

Question 16

How do mast cells contribute to innate immunity?

Accepted Answer

Mast cells express Toll-like r

Question 17

Which of the following tests is used to determine whether a particular allergen is responsible for asthma?

Accepted Answer

A) measure wheal-and-flare diameter after intradermal injection of allergen 
B) measure Arthus reaction diameter after intradermal injection of allergen 
C) inject a controlled amount of allergen intradermally and observe urticaria 
D) measure peak expiratory flow rate (PEFR)following inhalation of allergen 
E) measure eosinophils in nasal secretions following inhalation of allergen. 
A) measure wheal-and-flare diameter after intradermal injection of allergen 
B) measure Arthus reaction diameter after intradermal injection of allergen 
C) inject a controlled amount of allergen intradermally and observe urticaria 
D) measure peak expiratory flow rate (PEFR)following inhalation of allergen 
E) measure eosinophils in nasal secretions following inhalation of allergen.

Question 18

_____ released by TH2 cells promotes an elevated level of eosinophils in the circulation.

Accepted Answer

A) IL-4 
B) IL-13 
C) TNF-α 
D) FcγRII 
E) IL-5. 
A) IL-4 
B) IL-13 
C) TNF-α 
D) FcγRII 
E) IL-5.

Question 19

Prostaglandin D2 (PGD2)enhances all of the following except _____.

Accepted Answer

A) smooth muscle contraction 
B) chemotaxis of neutrophils 
C) increased vascular permeability 
D) vasodilation. 
A) smooth muscle contraction 
B) chemotaxis of neutrophils 
C) increased vascular permeability 
D) vasodilation.

Question 20

Which of the following is associated with eosinophilia? (Select all that apply.)

Accepted Answer

A) IL-5-induced proliferation 
B) endocardium damage 
C) neuropathy 
D) B-cell lymphoma 
E) decreased bone marrow function. 
A) IL-5-induced proliferation 
B) endocardium damage 
C) neuropathy 
D) B-cell lymphoma 
E) decreased bone marrow function.

_____ express FcεRI and contain granules containing inflammatory mediators.(Select all that apply.)

Which of the following are associated with soluble antigen? (Select all that apply.)

Which of the following is not mediated by antibodies?

Which of the following genetic polymorphisms is associated with a predisposition to asthma? (Select all that apply.)

Identify four different ways in which an individual may come into contact with an allergen and provide two examples of allergens for each type of contact.

All of the following are released immediately by mast cells after FcεRI cross-linking except _____.

Which of the following allergens is not likely to be encountered through inhalation?

Which of the following are matched correctly? (Select all that apply.)

What are the effects of histamine binding to the H₁ receptor on smooth muscle,mucosal epithelia,and the endothelial cells of blood vessels.

Some allergies can be treated by a procedure called desensitization. A.Explain two current approaches to desensitization. B.Explain the main disadvantage associated with each.

The wheal-and-flare inflammatory reaction is an example of

A.Explain why it is essential that FcεRI and Fcε RII are not able to bind simultaneously to the same IgE molecule. B.Why does simultaneous binding not occur?

Which of the following is associated with type III hypersensitivity?

How do mast cells contribute to innate immunity?

Which of the following tests is used to determine whether a particular allergen is responsible for asthma?

_____ released by T_H2 cells promotes an elevated level of eosinophils in the circulation.

Prostaglandin D₂ (PGD₂)enhances all of the following except _____.

Which of the following is associated with eosinophilia? (Select all that apply.)

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Cancer and Its Interactions With the Immune System

Filters

Exam 14: Ige-Mediated Immunity and Allergy

_____ express FcεRI and contain granules containing inflammatory mediators.(Select all that apply.)

Which of the following are associated with soluble antigen? (Select all that apply.)

Which of the following is not mediated by antibodies?

Which of the following genetic polymorphisms is associated with a predisposition to asthma? (Select all that apply.)

Identify four different ways in which an individual may come into contact with an allergen and provide two examples of allergens for each type of contact.

All of the following are released immediately by mast cells after FcεRI cross-linking except _____.

Which of the following allergens is not likely to be encountered through inhalation?

Which of the following are matched correctly? (Select all that apply.)

What are the effects of histamine binding to the H1 receptor on smooth muscle,mucosal epithelia,and the endothelial cells of blood vessels.

Some allergies can be treated by a procedure called desensitization. A.Explain two current approaches to desensitization. B.Explain the main disadvantage associated with each.

The wheal-and-flare inflammatory reaction is an example of

A.Explain why it is essential that FcεRI and Fcε RII are not able to bind simultaneously to the same IgE molecule. B.Why does simultaneous binding not occur?

Which of the following is associated with type III hypersensitivity?

How do mast cells contribute to innate immunity?

Which of the following tests is used to determine whether a particular allergen is responsible for asthma?

_____ released by TH2 cells promotes an elevated level of eosinophils in the circulation.

Prostaglandin D2 (PGD2)enhances all of the following except _____.

Which of the following is associated with eosinophilia? (Select all that apply.)

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Cancer and Its Interactions With the Immune System

Filters

What are the effects of histamine binding to the H₁ receptor on smooth muscle,mucosal epithelia,and the endothelial cells of blood vessels.

_____ released by T_H2 cells promotes an elevated level of eosinophils in the circulation.

Prostaglandin D₂ (PGD₂)enhances all of the following except _____.