During Protein Translocation to the ER

During protein translocation to the ER:

A) mRNA for ER-targeted protein is initially translated on ER-associated ribosomes.
B) emergence of the C-terminal signal sequence is bound by the ribonucleoprotein, SRP.
C) SRP binds to both the signal peptide and ribosome and halts translation.
D) SRP binds to SRP receptor and tethers the mRNA/ribosome to the nucleus.
E) the complex of SRP/SRP receptor/mRNA/ribosome migrates to the translocon, where signal peptidase cleavage facilitates SRP dissociation and translation continues.

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