Which Statement About Eukaryotic Gene Regulation Is CORRECT

Which statement about eukaryotic gene regulation is CORRECT?

A) Large polycistronic transcripts are common.
B) Most regulation is positive, involving activators rather than repressors.
C) Transcription and translation are mechanistically coupled.
D) Transcription does not involve promoters.
E) Transcription occurs without major changes in chromosomal organization.

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