Unequal Crossing Over During Prophase I Can Result in One

Unequal crossing over during prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of haemoglobin, so-called haemoglobin Lepore, exists in the human population. Haemoglobin Lepore has a deleted series of amino acids. If this mutated form was caused by unequal crossing over, what would be an expected consequence?

A) There should also be persons whose haemoglobin contains two copies of the series of amino acids that is deleted in haemoglobin Lepore.
B) Each of the genes in the haemoglobin gene family must show the same deletion.
C) The deleted gene must have undergone exon shuffling.
D) The deleted region must be located in a different area of the individual's genome.

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