In Colorectal Cancer, Several Genes Must Be Mutated in Order

In colorectal cancer, several genes must be mutated in order to contribute to a cell developing into a cancer cell, supporting Knudsen's hypothesis. Which of the following kinds of genes would you expect to be mutated?

A) genes coding for enzymes that act in the colon
B) genes involved in control of the cell cycle
C) genes that are especially susceptible to mutation
D) the same genes that Knudsen identified as associated with retinoblastoma
E) the genes of the bacteria that are abundant in the colon

Correct Answer:

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